FlyBase Aberration Report: Dmel\Df(2R)H3E1

General Information

Symbol

Df(2R)H3E1

Species

D. melanogaster

Name

FlyBase ID

FBab0024377

Feature type

chromosomal_deletion

Computed Breakpoints include

44D1-44D4;44F12

Features within 44D1--45A1 (Estimated cytology)

Genomic Maps

JBrowse

Sequence coordinates

2R:8,479,476..8,534,312 (Df(2R)H3E1:bk1)

(Cook et al., 2010.2.12)

2R:8,970,545..8,993,811 (Df(2R)H3E1:bk2)

(Cook et al., 2010.2.12)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

ptc^H3

(Matthews, 1996.2.2, Zhang et al., 1996)

Mutagen

X ray

(Matthews, 1996.2.2, Zhang et al., 1996)

Class of aberration (relative to wild type)

chromosomal_deletion

(Cook et al., 2010.2.12, FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Rao et al., 2001, Matthews, 1996.2.2, Zhang et al., 1996)

Breakpoints

44D;44F12

(Matthews, 1996.2.2, Zhang et al., 1996)

44D1-44D4;44F12

(Rao et al., 2001)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

bk1 << ptc << bk2 << wun

Genetic mapping information

Comments

Comments on Cytology

The left Df(2R)H3E1 breakpoint lies within mtt or to the right of mtt in the range 2R:4366981..4421817 (R5) (predicted cytology: 44D1-44D2).

(Cook et al., 2010.2.12)

The right Df(2R)H3E1 breakpoint lies within CG8213 or CG34350 or in the region between them, and lies in the range 2R:4858050..4881316 (R5) (predicted cytology: 44F12-45A1).

(Cook et al., 2010.2.12)

Left limit of break 1 from polytene analysis (FBrf0086252) Right limit of break 1 from inclusion of ptc (FBrf0089219) Limits of break 2 from polytene analysis (FBrf0086252)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Acsl

(Zhang et al., 2009)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (82)

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

The Df(2R)H3E1 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(2R)H3E1 results in 0.9% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Fails to complement Df(2R)44CE for lethality and show the ptc phenotype but germ cell migration is normal.

(Zhang et al., 1996)

Stocks (3)

201

108897

103338

w¹¹⁸ ; Df(2R)H3E1 / CyO

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Df H3E1

(Garver et al., 2006)

Df(2R)H3E1

(Tan et al., 2020, Rosa et al., 2018, Clough et al., 2014, Galindo et al., 2014, Szuplewski et al., 2012, Fernandes and Rao, 2011, Liu et al., 2011, Zhang et al., 2011, Cook et al., 2010.2.12, Ricardo and Lehmann, 2009, Zhang et al., 2009, Casso et al., 2008, Gilboa and Lehmann, 2006, Yi, 2006, Yi et al., 2006)

Df(2R)H3e1

(Zhang et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (37)

Report Sections

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