FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(1)su(s)R194
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General Information
Symbol
Df(1)su(s)R194
Species
D. melanogaster
Name
FlyBase ID
FBab0024817
Feature type
chromosomal_deletion
Also Known As
Df(1)R194
Computed Breakpoints include

1B9--10;[>1B13]

Features within 1B9--1B13
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Duffy et al., 1996)
Breakpoints

1B9-1B10;1B9-1B10

(Duffy et al., 1996)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << RpL36 << su(s) << bk2

Genetic mapping information
Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)
Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0086390) Left limit of break 2 from inclusion of l(1)1Bi (FBrf0086390)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Dredd
(Elrod-Erickson et al., 2000, Leulier et al., 2000)
Mybbp1A
(Duffy et al., 1996)
RpL36
(Duffy et al., 1996)
su(sable)
(Duffy et al., 1996)
Partially deleted / disrupted
Molecular Data
Completely deleted
RpL36
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    When clones of RpL36/+ (Df(1)su(s)R194/+) cells are generated in a wild-type background, making use of an RpL36+ transgene (RpL36+t4) linked to FRT80B, these cells are eliminated by cell competition.

    (Kale et al., 2015)

    Flies heterozygous for the deletion show a Minute bristle phenotype.

    (Marygold et al., 2007)

    Df(1)su(s)R194/+ clones are small and fragmented in mosaic eye imaginal discs containing two genotypes of cells; cells which are Df(1)su(s)R194/+ and cells in which the haplo-insufficiency of Df(1)su(s)R194/+ for RpL36 has been rescued by RpL36+t4. The Df(1)su(s)R194/+ clones are eliminated by cell competition and are not seen in adult eyes in these animals. In these animals, Df(1)su(s)R194/+ clones survive longer in the posterior of the eye (the first part of the eye to become postmitotic as the wave of eye differentiation begins), but are rare in the anterior of the eye (which proliferates for longer).

    (Tyler et al., 2007)

    Acts as a dosage sensitive maternal modifier of run : causes tergite defects in greater than 65% of run3 heterozygotes. Shows a dominant Minute phenotype: short fine bristles, delayed development and reduced viability.

    (Duffy et al., 1996)
    Stocks (0)
    Notes on Origin
    Discoverer

    R.A. Voelker and W. Steinhauer.

    (Duffy et al., 1996)
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (5)
    References (13)