FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2R)12
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General Information
Symbol
Df(2R)12
Species
D. melanogaster
Name
FlyBase ID
FBab0024847
Feature type
chromosomal_deletion
Computed Breakpoints include

46F-46F1;47A10

Features within 46F--47A10
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{lacW}B1-2-5
(Bhattacharya et al., 2002)
Mutagen
X ray
(Bhattacharya et al., 2002, Weber et al., 1995)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Weber et al., 1995)
Breakpoints

46E-46F;47A-47B

(Weber et al., 1995)
Causes alleles
psq12
(Quijano et al., 2016, Weber et al., 1995)
Carries alleles
Transposon Insertions
Formalized genetic data

l(2)46Ej << bk1 << Hr46 << bk2 hits psq

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from non-inclusion of Pfk (FBrf0098753) Right limit of break 1 from inclusion of Hr46 (FBrf0093560) Left limit of break 2 from inclusion of psq (FBrf0086124) Right limit of break 2 from non-inclusion of psq (FBrf0086124)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Lethal in combination with Df(2R)X1.

    (Bhattacharya et al., 2002)
    NOT in combination with other aberrations

    Homozygous lethal.

    (Bhattacharya et al., 2002, Weber et al., 1995)
    Stocks (2)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2R)12 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the suppressor maps to the tip of 2L rather than to the site of the deficiency.

    (Mason et al., 2004)
    Synonyms and Secondary IDs (2)
    References (17)