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General Information
D. melanogaster
FlyBase ID
Feature type
Also Known As
Df(3L)iro2, Df(3L)iro2, iro2, Df(3)iro2
Computed Breakpoints include
Deleted Segment
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
bk1 << ara << caup << bk2
Genetic mapping information
Comments on Cytology
Limits of break 1 from polytene analysis (FBrf0086419) Left limit of break 2 from inclusion of ara (FBrf0086419) Right limit of break 2 from polytene analysis (FBrf0086419)
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
The Df(3L)iro-2 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).
Heterozygosity for Df(3L)iro-2 results in 8.5% X chromosome nondisjunction and 3.4% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
Homozygous embryos have normal gut morphology.
In female D.simulans/D.melanogaster hybrids heterozygous for Df(3L)iro-2 the anterior notopleural bristle, presutural bristle, posterior notopleural bristle, anterior postalar bristle, posterior dorsocentral bristle, anterior dorsocentral bristle, and the posterior postalar bristle are lost at a high frequency compared to female D.simulans/D.melanogaster hybrid controls, when grown at 25oC. At 18oC only the posterior supraalar bristle and the anterior supraalar bristle are affected.
Homozygous lethal.
Stocks (3)
Notes on Origin
Balancer / Genotype Variants of the Aberration
Separable Components
Other Comments
Isolated as a mutation that alters the pattern of bristles when doubly heterozygous with Df(4)M101-62f.
Synonyms and Secondary IDs (9)
References (34)