Aberration Dmel\Df(2L)Dwee1-W05

General Information
Symbol	Dmel\Df(2L)Dwee1-W05	Species	D. melanogaster
Name		FlyBase ID	FBab0026801
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data
Sequence coordinates
Deleted segment	27C2--27C5
Duplicated segment
Computed Breakpoints include	27C2-27C3;27C4-27C5
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor	P{lacW}Hrb27C^k10413 (Price et al., 2000)
Mutagen	P-element activity (Price et al., 2000)
Class of aberration (relative to progenitor)	chromosomal_deletion (Beaton, 1997.3.4)
Breakpoints	27C2-27C3;27C4-27C5 (Beaton, 1997.3.4)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0092781) Cytology based upon complementation. (Beaton, 1997.3.4)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Hrb27C (BDGP Project Members, 1994-1999, Spradling et al., 1999, Price et al., 2000) l(2)k00213 (BDGP Project Members, 1994-1999, Price et al., 2000) l(2)EL3 (Price et al., 2000) l(2)DL1 (Price et al., 2000)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Rca1 (BDGP Project Members, 1994-1999, Spradling et al., 1999) Coprox (BDGP Project Members, 1994-1999, Spradling et al., 1999) smt3 (BDGP Project Members, 1994-1999, Spradling et al., 1999) l(2)k14206 (BDGP Project Members, 1994-1999, Spradling et al., 1999) S(CycE^JP)2.8 (Brumby et al., 2004) l(2)k09022 (BDGP Project Members, 1994-1999, Spradling et al., 1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Homozygous animals derived from heterozygous parents die late in embryogenesis with no obvious mitotic abnormalities. No eggs are produced from females containing homozygous germline clones. (Price et al., 2000)
Position Effect Variegation Data

Stocks ( 2 )
Kyoto	108220 Df(2L)Dwee1-W05/CyO; P{ftz/lacC}1
Bloomington	5420 w^*; Df(2L)Dwee1-W05/CyO; P{ftz/lacC}1
Notes on Origin
Discoverer	S. Campbell. (Beaton, 1997.3.4)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(2L)Dwee1^w05 (Brumby et al., 2004) Df(2L)Dwee1-W05 Df(2L)dwee^wo5 (Stumpff et al., 2004) Df(2L)Dwee^wo5
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	Stumpff et al., 2005, Curr. Biol. 15(17): 1525--1534 Drosophila Wee1 Interacts with Members of the gammaTURC and Is Required for Proper Mitotic-Spindle Morphogenesis and Positioning. [FBrf0187336] Brumby et al., 2004, Genetics 168(1): 227--251 A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila. [FBrf0180291] Stumpff et al., 2004, Curr. Biol. 14(23): 2143--2148 Drosophila Wee1 kinase regulates Cdk1 and mitotic entry during embryogenesis. [FBrf0183813] Price et al., 2000, Genetics 155(1): 159--166 Drosophila wee1 has an essential role in the nuclear divisions of early embryogenesis. [FBrf0127282] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Personal communication to FlyBase	Beaton, 1997.3.4, Update: Deficiencies. Update: Deficiencies. [FBrf0092781]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Computer file	BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]