Aberration Dmel\Df(2R)RM2-1

General Information
Symbol	Dmel\Df(2R)RM2-1	Species	D. melanogaster
Name		FlyBase ID	FBab0026845
Feature type	chromosomal_deletion

Computed Breakpoints include	54F2;56A1
Deleted segment	54F2--56A1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Beaton, 1997.3.4)
Breakpoints	54F2;56A1 (Beaton, 1997.3.4)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0092781)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	edl (Spradling et al., 1999, BDGP Project Members, 1994-1999) grh (Spradling et al., 1999, BDGP Project Members, 1994-1999) pAbp (Spradling et al., 1999, BDGP Project Members, 1994-1999) Prp19 (Spradling et al., 1999, BDGP Project Members, 1994-1999) sbb (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	l(2)03709 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)08717 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)08770 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)gl (Mason et al., 2004) l(2)k06106 (BDGP Project Members, 1994-1999) l(2)k07509 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k08931 (BDGP Project Members, 1994-1999) l(2)k09021 (BDGP Project Members, 1994-1999) l(2)k09924 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k11311 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k14601 (BDGP Project Members, 1994-1999) l(2)s1864 (BDGP Project Members, 1994-1999) olf186-F (Spradling et al., 1999, BDGP Project Members, 1994-1999) POSH (Spradling et al., 1999, BDGP Project Members, 1994-1999) sub (Giunta et al., 2002)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 2 )
Bloomington	5426 w^*; Df(2R)RM2-1/CyO, P{sevRas1.V12}FK1
Kyoto	108226 w^*; Df(2R)RM2-1/CyO, P{sevRas1.V12}FK1
Notes on Origin
Discoverer	F. Karim. (Beaton, 1997.3.4)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(2R)RM2-1 chromosome acts as a dominant moderate suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by a combination of nonsuppressing deficiencies and deficiencies with suppressors that map to the 2L tip. (Mason et al., 2004)
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(2R)RM2-1 (Riedl et al., 2007, Casso et al., 2008)
Name Synonym
Secondary FlyBase IDs

References ( 9 )
Research paper	Casso et al., 2008, Genetics 178(3): 1399--1413 A screen for modifiers of hedgehog signaling in Drosophila melanogaster identifies swm and mts. [FBrf0205418] Riedl et al., 2007, Fly 1(1): 23--32 Genetic and behavioral analysis of natural variation in Drosophila melanogaster pupation position. [FBrf0200063] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Ward et al., 2003, Genetics 165(3): 1397--1415 Genetic modifier screens in Drosophila demonstrate a role for Rho1 signaling in ecdysone-triggered imaginal disc morphogenesis. [FBrf0167639] Giunta et al., 2002, Genetics 160(4): 1489--1501 subito encodes a kinesin-like protein required for meiotic spindle pole formation in Drosophila melanogaster. [FBrf0147060] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Personal communication to FlyBase	Beaton, 1997.3.4, Update: Deficiencies. Update: Deficiencies. [FBrf0092781] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]