Aberration Dmel\In(1)w^is

General Information
Symbol	Dmel\In(1)w^is	Species	D. melanogaster
Name		FlyBase ID	FBab0027226
Feature type	chromosomal_inversion

Computed Breakpoints include	3C;20F
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	w^is (Rasmuson-Lestander et al., 1993)
Mutagen	spontaneous (Rasmuson-Lestander et al., 1993)
Class of aberration (relative to progenitor)	chromosomal_inversion (Rasmuson-Lestander et al., 1993)
Breakpoints	3C;20F (Rasmuson-Lestander et al., 1993)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	Inversion placing the w^is mutation close to heterochromatin. The distal breakpoint is distal to w, and the proximal breakpoint is located proximal to or proximally within the bb locus. (Rasmuson-Lestander et al., 1993) All limits from polytene analysis (FBrf0068645)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	The z¹ In(1)w^is eye colour phenotype is suppressed by Df(YS)B4, Df(YL)S6 and Df(YS)S12, and enhanced by Df(YL)G22 and Df(YL)S10. (Rasmuson-Lestander et al., 1993)
NOT in combination with other aberrations	The male offspring of In(1)w^is z¹ females mated to wild-type males have yellow-white variegated eyes. z¹ In(1)w^is / z¹ w⁺ females have red-orange or orange-yellow variegated eyes. Introduction of Su(z)2^unspecified into z¹ In(1)w^is flies does not alter the background level of pigmentation (white) but darkens the yellow flecks in the eye to orange or red. (Rasmuson-Lestander et al., 1993)
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The w gene on the In(1)w^is chromosome is influenced by position effect variegation and also regulated by chromosome pairing-dependent z¹-mediated repression. (Rasmuson-Lestander et al., 1993)
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	In(1)w^is
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Rasmuson-Lestander et al., 1993, Hereditas 119(3): 209--218 Position-effect variegation and z¹ mediated white repression in the In(1)w^is system in Drosophila melanogaster. [FBrf0068645]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]

Aberration Dmel\In(1)wis

Aberration Dmel\In(1)w^is