FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2R)IR7
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General Information
Symbol
Df(2R)IR7
Species
D. melanogaster
Name
FlyBase ID
FBab0027372
Feature type
chromosomal_deletion
Computed Breakpoints include

h41;h41

Features within h41--h41
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
IR-hybrid dysgenesis
(Dimitri et al., 1997)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Dimitri et al., 1997)
Breakpoints

h41;h41

(Dimitri et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << l(2)41Aa << rl << bk2

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0094580) Right limit of break 1 from inclusion of l(2)41Aa (FBrf0094580) Left limit of break 2 from inclusion of l(2)41Aa (FBrf0094580) Right limit of break 2 from polytene analysis (FBrf0094580)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
rl
(Dimitri et al., 1997)
Yeti
(Cenci et al., 2003, Dimitri et al., 1997)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Df(2R)IR7/Df(2R)B mutant larvae have abnormal wing discs. Df(2R)B/Df(2R)IR7 mutant larval neuroblast cells exhibit a higher anaphase/metaphase ratio than wild-type cells. The total number of Df(2R)B/Df(2R)IR7 larval neuroblast cells undergoing mitosis is reduced compared to wild-type cells (mitotic index of 0.41 vs 0.81). 25% of Df(2R)B/Df(2R)IR7 mutant larval spermatids carry micronuclei. 12% of Df(2R)IR7/Df(2R)B mutant larval spermatids have large Nebenkerns associated with either two or four nuclei or micronuclei. In 30% of Df(2R)IR7/Df(2R)B mutant larval spermatids, bivalents do not condense properly and chromatin filaments are visible along the three major dots of chromatin. In Df(2R)B/Df(2R)IR7 mutant larval spermatids, 28% of chromosomes are seen to be lagging during anaphase/telophase I, while 21% lag during anaphase/telophase II.

    (Cenci et al., 2003)
    NOT in combination with other aberrations
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    Df(2R)IR7
    Df(2Rh)IR7
    (Cenci et al., 2003)
    DfIR7
    (Cenci et al., 2003)
    l(2Rh)IR7
    (Dimitri et al., 1997)
    Name Synonyms
    Secondary FlyBase IDs
      References (3)