Aberration Dmel\Df(3L)ZP1

General Information
Symbol	Dmel\Df(3L)ZP1	Species	D. melanogaster
Name		FlyBase ID	FBab0027425
Feature type	chromosomal_deletion
Also Known As	Df(3L)ZP-1

Computed Breakpoints include	66A17-66A20;66C1-66C5
Deleted segment	66A17--66C5
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	Tp(1;3)TE67A (Maroy, 1997.10.17)
Mutagen	X ray (Maroy, 1997.10.17)
Class of aberration (relative to progenitor)	chromosomal_deletion (Maroy, 1997.10.17, Deak et al., 1997)
Breakpoints	66A17-66A20;66C1-66C5 (Maroy, 1997.10.17, Deak et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << l(3)DTS4 << bk2
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0098953)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Arp3 (Rajan et al., 2009, Berger et al., 2008) carbuncle (Ghabrial et al., 2011) ivy (Ghabrial et al., 2011) l(3)DTS4 (Maroy, 1997.10.17) l(3)S002309 (Deak et al., 1997) l(3)S004209a (Deak et al., 1997) l(3)S007608 (Szeged Stock Center, 1998-, Deak et al., 1997) l(3)S036401b (Deak et al., 1997) l(3)S045902 (Szeged Stock Center, 1998-) l(3)S090314 (Szeged Stock Center, 1998-, Deak et al., 1997) l(3)S094003 (Szeged Stock Center, 1998-) l(3)S103012b (Szeged Stock Center, 1998-, Deak et al., 1997) l(3)S104210a (Deak et al., 1997) l(3)S117902 (Deak et al., 1997) l(3)S117913 (Deak et al., 1997) l(3)S118602a (Deak et al., 1997) l(3)S118608 (Deak et al., 1997) l(3)S143517 (Deak et al., 1997) l(3)S144405 (Szeged Stock Center, 1998-) MED24 (Wang et al., 2008)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Ank2 (Koch et al., 2008) l(3)psg2 (Wang et al., 2008) l(3)S002309 (Szeged Stock Center, 1998-) pbl (Szeged Stock Center, 1998-) rhea (Levi et al., 2006)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Fails to complement Tp(1;3)TE67A, Df(3L)66C-G28 and Df(3L)pbl-X1. (Maroy, 1997.10.17)
NOT in combination with other aberrations	The Df(3L)ZP1 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Heterozygosity for Df(3L)ZP1 results in 1.0% X chromosome nondisjunction and 0.7% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003)
Stocks ( 2 )
Bloomington	5877 w¹; Df(3L)ZP1/TM3, Sb¹ Ser¹
Kyoto	108475 w¹; Df(3L)ZP1/TM3, Sb¹ Ser¹
Notes on Origin
Discoverer	P. Zavorszky. (Maroy, 1997.10.17)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(3L)ZP-1 (Deak et al., 1997, Levi et al., 2006, Levi et al., 2006) Df(3L)ZP1 (Rajan et al., 2009, Koch et al., 2008, Wang et al., 2008, Berger et al., 2008, Slack et al., 2006, Ghabrial et al., 2011)
Name Synonym
Secondary FlyBase IDs

References ( 15 )
Research paper	Ghabrial et al., 2011, PLoS Genet. 7(7): e1002087 A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. [FBrf0214368] Rajan et al., 2009, Nat. Cell Biol. 11(7): 815--824 The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors. [FBrf0208249] Berger et al., 2008, J. Cell Sci. 121(8): 1303--1313 WASP and SCAR have distinct roles in activating the Arp2/3 complex during myoblast fusion. [FBrf0204821] Koch et al., 2008, Neuron 58(2): 210--222 Drosophila ankyrin 2 is required for synaptic stability. [FBrf0204749] Wang et al., 2008, Genetics 180(1): 269--281 A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila. [FBrf0207097] Levi et al., 2006, Development 133(12): 2383--2393 Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization. [FBrf0193035] Slack et al., 2006, BMC Genet. 7: 33 A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions. [FBrf0192335] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Harris et al., 2003, Genetics 165(2): 637--652 A deficiency screen of the major autosomes identifies a gene (matrimony) that is haplo-insufficient for achiasmate segregation in Drosophila oocytes. [FBrf0167662] Presgraves, 2003, Genetics 163(3): 955--972 A fine-scale genetic analysis of hybrid incompatibilities in Drosophila. [FBrf0158988] Deak et al., 1997, Genetics 147(4): 1697--1722 P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: correlation of physical and cytogenetic maps in chromosomal region 86E-87F. [FBrf0099762]
Erratum	Levi et al., 2006, Development 133(14): 2781 Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization (vol 133, pg 2383, 2006). [FBrf0193155]
Personal communication to FlyBase	Maroy, 1997.10.17, ZP1. ZP1. [FBrf0098953]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Stock list	Szeged Stock Center, 1998-, Szeged Stock Center P-element collection. (Computer file) Szeged Stock Center P-element collection. (Computer file) [FBrf0111308]