Aberration Dmel\Dp(1;Y)BSC1

General Information
Symbol	Dmel\Dp(1;Y)BSC1	Species	D. melanogaster
Name		FlyBase ID	FBab0029201
Feature type	interchromosomal_duplication

Computed Breakpoints include
Duplicated segment	10C1--11D8 (Observed cytology)
Sequence coordinates
Member of large scale dataset(s)	Dps(X)BSC_set1 Series of Dp(1;Y) stocks carrying segments of the X chromosome on the tip of Y chromosome; in an isogenic background. At the time of publication (FBrf0212582), the Dp(1;Y) collection provided a minimum of 78% coverage with duplication breakpoints spaced a median of nine genes apart. After generating all the Dp(1;Y)BSC chromosomes as described in FBrf0212582, we calculated the minimal euchromatic coverage of the X chromosome provided by these duplications as 97.0%. (Cook et al., 2010, Cook, 2012.8.8)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	C(1;Y)sc^260-14 (Gornek et al., 2000.2.4)
Mutagen	gamma ray (Gornek et al., 2000.2.4)
Class of aberration (relative to progenitor)	chromosomal_deletion (Gornek et al., 2000.2.4)
Breakpoints	10C1-10C2;h26-h32 (Gornek et al., 2000.2.4)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	The cytologically observed breakpoints may not represent the full extent of the duplicated segment, because euchromatic bands juxtaposed to centric heterochromatin may not be visible. (Cook et al., 2010) No mutations distal to l(1)G0241 are rescuable by Dp(1;Y)BSC1. The polytene bands closest to the chromocenter in squashes appear to be from region 10. (Gornek et al., 2000.2.4)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated	dy (Gornek et al., 2000.2.4, Cook et al., 2010) fw (Gornek et al., 2000.2.4, Cook et al., 2010) Hsc70-3 (Gornek et al., 2000.2.4, Cook et al., 2010) l(1)G0241 (Gornek et al., 2000.2.4, Cook et al., 2010) m (Gornek et al., 2000.2.4, Cook et al., 2010) qs (Gornek et al., 2000.2.4, Cook et al., 2010) Smr (Cook et al., 2010, Gornek et al., 2000.2.4) tsg (Gornek et al., 2000.2.4, Cook et al., 2010) y (Gornek et al., 2000.2.4)
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Male fertile. (Gornek et al., 2000.2.4)
Stocks ( 1 )
Bloomington	5596 Dp(1;Y)BSC1, y⁺/w^67c23 P{lacW}Smr^G0060/C(1)RA, y¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Dp(1;Y)BSC1 (Mukai et al., 2007, Metzstein and Krasnow, 2006, Cook et al., 2010)
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Cook et al., 2010, Genetics 186(4): 1095--1109 A new resource for characterizing X-linked genes in Drosophila melanogaster: systematic coverage and subdivision of the X chromosome with nested, Y-linked duplications. [FBrf0212582] Mukai et al., 2007, Mech. Dev. 124(7-8): 570--583 MAMO, a maternal BTB/POZ-Zn-finger protein enriched in germline progenitors is required for the production of functional eggs in Drosophila. [FBrf0202210] Metzstein and Krasnow, 2006, PLoS Genet. 2(12): e180 Functions of the nonsense-mediated mRNA decay pathway in Drosophila development. [FBrf0194265]
Personal communication to FlyBase	Cook, 2012.8.8, Duplication coverage of X euchromatin provided by Dp(1;Y)BSC chromosomes. Duplication coverage of X euchromatin provided by Dp(1;Y)BSC chromosomes. [FBrf0219194] Gornek et al., 2000.2.4, Dp(1;Y)s for the 10C to 11D Region. Dp(1;Y)s for the 10C to 11D Region. [FBrf0125111]
FlyBase analysis	Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site). Lines in aberration datasets (files on ftp site). [FBrf0219195]