Aberration Dmel\Df(3L)Fpa1

General Information
Symbol	Dmel\Df(3L)Fpa1	Species	D. melanogaster
Name		FlyBase ID	FBab0029365
Feature type	chromosomal_deletion

Computed Breakpoints include
Deleted segment	61D1--61F2
Map ( GBrowse )	Untitled Document Error No matching regions found.
Sequence coordinates	3L:1,168,218..1,174,011 [-] (Df(3L)Fpa1:bk2) (Couderc et al., 2002)
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray (Couderc et al., 2002)
Class of aberration (relative to progenitor)	chromosomal_deletion (Couderc et al., 2002, Liebl et al., 2000)
Breakpoints	61D1-61D2;61F1-61F2 (Awasaki et al., 2000, Liebl et al., 2000) 61D1;61F1-61F2 (Couderc et al., 2002)
Causes alleles	bab2^Fpa1 (Couderc et al., 2002)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	bab1 (Couderc et al., 2002) bab2 (Couderc et al., 2002) emc (Saito et al., 2002) Glut1 (Saito et al., 2002) l(3)61Db-S (Saito et al., 2002) l(3)61Dc (Saito et al., 2002) l(3)61Dd (Saito et al., 2002) l(3)61De (Saito et al., 2002) l(3)61Df (Saito et al., 2002) l(3)00835 (Saito et al., 2002) trio (Saito et al., 2002, Awasaki et al., 2000, Liebl et al., 2000)
Molecular Data
Completely deleted	trio (Saito et al., 2002)
Genes NOT Deleted / Disrupted
Complementation Data
	Aplip1 (Horiuchi et al., 2005)
Molecular Data
	bab2 (Wei et al., 2003)
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(3L)Fpa1/Df(3L)Fpa2 flies are semi-lethal. (Wei et al., 2003) Df(3L)Fpa1/Df(3L)bab-PG embryos show severely disrupted patterns of axon wiring, with no longitudinal fascicles being visibly Fas2 staining. (Saito et al., 2002)
NOT in combination with other aberrations
Stocks ( 0 )

Notes on Origin
Discoverer
	Heterozygous females have a pigmentation defect. (Couderc et al., 2002)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(3L)Fpa1 (Saito et al., 2002, Wei et al., 2003) Df(3L)FpaI (Forsthoefel et al., 2005) Df(3L)Fpal
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	Forsthoefel et al., 2005, Development 132(8): 1983--1994 The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila. [FBrf0183931] Horiuchi et al., 2005, Curr. Biol. 15(23): 2137--2141 APLIP1, a kinesin binding JIP-1/JNK scaffold protein, influences the axonal transport of both vesicles and mitochondria in Drosophila. [FBrf0190020] Wei et al., 2003, Genome 46(6): 1049--1058 Functional genomic analysis of the 61D-61F region of the third chromosome of Drosophila melanogaster. [FBrf0167686] Couderc et al., 2002, Development 129(10): 2419--2433 The bric a brac locus consists of two paralogous genes encoding BTB/POZ domain proteins and acts as a homeotic and morphogenetic regulator of imaginal development in Drosophila. [FBrf0146992] Saito et al., 2002, Mol. Genet. Genomics 268(4): 446--454 Genetic analyses of essential genes in cytological region 61D1-2 to 61F1-2 of Drosophila melanogaster. [FBrf0155968] Awasaki et al., 2000, Neuron 26(1): 119--131 The Drosophila trio plays an essential role in patterning of axons by regulating their directional extension. [FBrf0126995] Liebl et al., 2000, Neuron 26(1): 107--118 Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding. [FBrf0127511]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]

Aberration Dmel\Df(3L)Fpa1

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