Aberration Dmel\Df(3L)E44

General Information
Symbol	Dmel\Df(3L)E44	Species	D. melanogaster
Name		FlyBase ID	FBab0029477
Feature type	chromosomal_deletion

Computed Breakpoints include
Deleted segment	69D2--69E5
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Carpenter and Sun, 2000.12.22)
Breakpoints	69D2;69E3-69E5 (Carpenter and Sun, 2000.12.22)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	vih (Mathe et al., 2004)
Molecular Data
Completely deleted	sti (Naim et al., 2004)
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	In(3L)A54/Df(3L)E44 and In(3L)A54/Df(3L)F10 transheterozygotes recessive phenotypes are seen. These include missing mid-thorax, reduced eyes and aristae, and held-up wings. These recessive phenotypes may reflect effects of the In(3L)A54 69BC inversion breakpoint on gv and eyg. Viability is low with many uneclosed pupae. When dissected, these pupae are headless (except for the presence of palps) or have very reduced heads. They also show the thoracic defects seen in the viable escapers. (Carpenter, 2002.4.2) Fails to complement Df(3L)F10. (Carpenter and Sun, 2000.12.22)
NOT in combination with other aberrations	The Df(3L)E44 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Stocks ( 2 )
Bloomington	5915 Df(3L)E44/TM3, Ser¹
Kyoto	108484 Df(3L)E44/TM3, Ser¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(3L)E44
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	D'Avino et al., 2004, J. Cell Biol. 166(1): 61--71 Mutations in sticky lead to defective organization of the contractile ring during cytokinesis and are enhanced by Rho and suppressed by Rac. [FBrf0179178] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Mathe et al., 2004, Curr. Biol. 14(19): 1723--1733 The E2-C vihar is required for the correct spatiotemporal proteolysis of cyclin B and itself undergoes cyclical degradation. [FBrf0180066] Naim et al., 2004, Mol. Biol. Cell 15(11): 5053--5063 Drosophila citron kinase is required for the final steps of cytokinesis. [FBrf0180505] Yan and Macdonald, 2004, Genetics 168(3): 1433--1442 Genetic interactions of Drosophila melanogaster arrest reveal roles for translational repressor Bruno in accumulation of Gurken and activity of Delta. [FBrf0180283]
Personal communication to FlyBase	Carpenter, 2002.4.2, In(3L)A54 and cu<up>2</up>. In(3L)A54 and cu². [FBrf0149628] Carpenter and Sun, 2000.12.22, Df(3L)F10 and Df(3L)E44. Df(3L)F10 and Df(3L)E44. [FBrf0133288]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]