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General Information
D. melanogaster
FlyBase ID
Feature type
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Embryos derived from lok null mothers (Df(2L)pr2b/Df(2L)be408 females carrying P{CG10728+tMa} to rescue vls function and P{barr+tMa} to rescue barr function) have an average of 24.5 pole cells/embryo compared to the wild-type number of 37.3 pole cells/embryo. The progeny of the lok null flies are viable and fertile, they show no increase in the rate of X chromosome nondisjunction compared to controls and females show no defects in meiotic recombination frequency. lok null larvae are not more sensitive to methyl methanesulfonate or hydroxyurea than control larvae. Irradiation does not result in a delay of entry into mitosis in lok null embryos, in contrast to wild-type embryos.

    Viable and female fertile in combination with Df(2L)Sd37.

    NOT in combination with other aberrations
    Stocks (0)
    Notes on Origin

    Separable from: a second site lethal mutation elsewhere on the chromosome.

    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments

    Deficiency affecting barr, lok and vls.

    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (5)