FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2R)ED1
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General Information
Symbol
Df(2R)ED1
Species
D. melanogaster
Name
FlyBase ID
FBab0029713
Feature type
chromosomal_deletion
Computed Breakpoints include

[53E4-53E4];[53F8-53F8];

Features within 53E4--53F8
Genomic Maps
Sequence coordinates
2R:17,026,727..17,026,727 (Df(2R)ED1:bk1)
(DrosDel Project, 2007.6.25)
2R:17,097,322..17,097,322 (Df(2R)ED1:bk2)
(DrosDel Project, 2007.6.25)
Member of large scale dataset(s)
Dfs_DrosDel_set1

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.

(Ryder et al., 2007)
Nature of Aberration
Cytological Order
Progenitor
P{RS3r}CB-0140-3
(Ryder et al., 2004, Ryder, 2003.6.17, Roote, 2002.2.6)
P{RS5r}5-HA-1118
(Ryder et al., 2004, Ryder, 2003.6.17, Roote, 2002.2.6)
Mutagen
FLPase
(Ryder et al., 2004, Ryder, 2003.6.17, Roote, 2002.2.6)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Ryder et al., 2004, Ryder, 2003.6.17, Roote, 2002.2.6)
Breakpoints

53E4;53F8

(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P{3'.RS5+3.3'}ED1
(Ryder et al., 2004, Ryder, 2003.6.17, Roote, 2002.2.6)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions.

(Ryder and Roote, 2005.11.4)

Confirmed by PCR (using the 3-step process described on http://www.drosdel.org.uk/del_confirm.php).

(Ryder and Roote, 2004.11.10)

Limits computationally determined from location of progenitor P insertion on genome sequence between P{lacW}l(2)k11405k11405&P{EP}EP641 and P{lacW}l(2)k10815k10815

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
GstS1
(Whitworth et al., 2005)
RhoGEF2
(Ryder and Roote, 2004.11.10, Ryder et al., 2004, Roote, 2002.9.18)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (19)
Phenotypic Data
In combination with other aberrations

Inferred to overlap with: Df(2R)P803-Delta15.

(Ryder and Roote, 2004.11.10)

Lethal in combination with Df(2R)P803-Δ15.

(Ryder et al., 2004)

Lethal in combination with In(2LR)DTD99. Lethal in combination with Df(2R)P803-Δ15.

(Roote, 2002.2.6)
NOT in combination with other aberrations

Heterozygotes show resistance to halothane compared to controls.

(Alone et al., 2009)
Stocks (3)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Df(2R)ED1
(Vrailas-Mortimer et al., 2021, Hope et al., 2019, Wang and Baker, 2015, FlyBase Curators, 2008, Mills et al., 2006)
Df_2R_ED1
(Nelson et al., 2016)
ED1
(Alone et al., 2009)
Name Synonyms
Secondary FlyBase IDs
    References (17)