Aberration Dmel\Df(3L)BSC13

General Information
Symbol	Dmel\Df(3L)BSC13	Species	D. melanogaster
Name		FlyBase ID	FBab0029723
Feature type	chromosomal_deletion

Computed Breakpoints include
Deleted segment	66B12--66D4
Sequence coordinates
Member of large scale dataset(s)	Dfs_BSC_set1 A set of ~50 targeted deficiencies created by exploiting hybrid element insertion (HEI) and resolution; designed to fill gaps in deletion coverage. (Parks et al., 2004)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{EP}ergic53^EP3212 (Deal and Cook, 2002.2.25, Parks et al., 2004) P{lacW}Nmt^j1C7 (Deal and Cook, 2002.2.25, Parks et al., 2004)
Mutagen	Delta2-3 (Deal and Cook, 2002.2.25) recombination (Deal and Cook, 2002.2.25)
Class of aberration (relative to progenitor)	chromosomal_deletion (Deal and Cook, 2002.2.25, Parks et al., 2004)
Breakpoints	66B12-66C1;66D2-66D4 (Parks et al., 2004) 66B12-66C14;66D2-66D4 (Deal and Cook, 2002.2.25)
Causes alleles
Carries alleles	e¹ (Deal and Cook, 2002.2.25) rho^ve-1 (Deal and Cook, 2002.2.25)
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Gug (Deal and Cook, 2002.2.25) l(3)B27 (Slack et al., 2006)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	MED24 (Wang et al., 2008) rhea (Levi et al., 2006)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Lethal in combination with T(2;3)E(da). (Deal and Cook, 2002.2.25)
NOT in combination with other aberrations	The distal half of the salivary gland turns but the proximal half does not in embryos homozygous for Df(3L)BSC13 by stage 14. (Jattani et al., 2009) The Df(3L)BSC13 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Heterozygosity for Df(3L)BSC13 results in 50.8% X chromosome nondisjunction and 11.9% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003)
Stocks ( 1 )
Kyoto	108789 Df(3L)BSC13, rho^ve-1 e¹/TM2, p^p
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The miniwhite markers from both P{lacW}Nmt^j1C7 and P{EP}ergic53^EP3212 were deleted or disrupted. (Mason, 2004.11.26)
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(3L)BSC13 (Levi et al., 2006, Levi et al., 2006, Goodliffe et al., 2007, Jattani et al., 2009, Wang et al., 2008, Slack et al., 2006)
Name Synonym
Secondary FlyBase IDs

References ( 15 )
Research paper	Jattani et al., 2009, Dev. Dyn. 238(4): 853--863 Deficiency screen identifies a novel role for beta 2 tubulin in salivary gland and myoblast migration in the Drosophila embryo. [FBrf0207774] Wang et al., 2008, Genetics 180(1): 269--281 A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila. [FBrf0207097] Goodliffe et al., 2007, BMC Mol. Biol. 8: 40 Coordinated regulation of Myc trans-activation targets by polycomb and the trithorax group protein Ash1. [FBrf0201535] Levi et al., 2006, Development 133(12): 2383--2393 Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization. [FBrf0193035] Slack et al., 2006, BMC Genet. 7: 33 A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions. [FBrf0192335] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Parks et al., 2004, Nat. Genet. 36(3): 288--292 Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome. [FBrf0175003] Yan and Macdonald, 2004, Genetics 168(3): 1433--1442 Genetic interactions of Drosophila melanogaster arrest reveal roles for translational repressor Bruno in accumulation of Gurken and activity of Delta. [FBrf0180283] Harris et al., 2003, Genetics 165(2): 637--652 A deficiency screen of the major autosomes identifies a gene (matrimony) that is haplo-insufficient for achiasmate segregation in Drosophila oocytes. [FBrf0167662]
Supplementary material	Parks et al., 2004, Nature Genetics 36(3): Supplementary Table 1: Deletions generated at Bloomington between trans-heterozygous P element insertions. [FBrf0179070]
Erratum	Levi et al., 2006, Development 133(14): 2781 Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization (vol 133, pg 2383, 2006). [FBrf0193155]
Personal communication to FlyBase	Mason, 2004.11.26, Miniwhite in BSC deletions. Miniwhite in BSC deletions. [FBrf0179886] Deal and Cook, 2002.2.25, Isolation and characterization of Df(3L)BSC13. Isolation and characterization of Df(3L)BSC13. [FBrf0145643]
FlyBase analysis	Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site). Lines in aberration datasets (files on ftp site). [FBrf0219195] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]