Aberration Dmel\Df(2R)BSC19

General Information
Symbol	Dmel\Df(2R)BSC19	Species	D. melanogaster
Name		FlyBase ID	FBab0029795
Feature type	chromosomal_deletion

Computed Breakpoints include
Deleted segment	56F12--57A4
Sequence coordinates
Member of large scale dataset(s)	Dfs_BSC_set1 A set of ~50 targeted deficiencies created by exploiting hybrid element insertion (HEI) and resolution; designed to fill gaps in deletion coverage. (Parks et al., 2004)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{EP}CG10444^EP951 (Deal-Herr and Cook, 2002.7.15, Parks et al., 2004) P{lacW}l(2)s4831^s4831 (Deal-Herr and Cook, 2002.7.15, Parks et al., 2004)
Mutagen	Delta2-3 (Deal-Herr and Cook, 2002.7.15) recombination (Deal-Herr and Cook, 2002.7.15)
Class of aberration (relative to progenitor)	chromosomal_deletion (Deal-Herr and Cook, 2002.7.15, Parks et al., 2004)
Breakpoints	56F12-56F14;57A4 (Deal-Herr and Cook, 2002.7.15, Parks et al., 2004)
Causes alleles
Carries alleles	bw¹ (Deal-Herr and Cook, 2002.7.15) cn¹ (Deal-Herr and Cook, 2002.7.15)
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Fails to complement Df(2R)BSC400. (Christensen et al., 2007.10.29) Inferred to overlap with: Df(2R)BSC400. (Christensen et al., 2007.10.29)
NOT in combination with other aberrations	Homozygous Df(2R)BSC19 mutant embryos produce a phenotype in which only the dorsal branch of the abdominal segmental nerve (SNa) is absent or malformed. In 25% of abdominal hemisegments one or more of the dorsal branch target muscles is not present, and this could account for the absence of the branch in these hemisegments. (Wright et al., 2010) The Df(2R)BSC19 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Stocks ( 2 )
Bloomington	6609 Df(2R)BSC19, cn¹ bw¹/SM6a
Kyoto	108849 Df(2R)BSC19, cn¹ bw¹/SM6a
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The miniwhite markers from both P{EP}CG10444^EP951 and P{lacW}l(2)s4831^s4831 were deleted or disrupted. (Mason, 2004.11.26)
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(2R)BSC19 (Christensen et al., 2007.10.29, Wright et al., 2010) Df(2R) BSC 19 (Fiehler and Wolff, 2008)
Name Synonym
Secondary FlyBase IDs

References ( 10 )
Research paper	Wright et al., 2010, PLoS ONE 5(8): e12288 Systematic screening of Drosophila deficiency mutatations for embryonic phenotypes and orphan receptor ligands. [FBrf0211648] Fiehler and Wolff, 2008, Dev. Biol. 313(2): 533--544 Nemo is required in a subset of photoreceptors to regulate the speed of ommatidial rotation. [FBrf0203152] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Parks et al., 2004, Nat. Genet. 36(3): 288--292 Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome. [FBrf0175003]
Supplementary material	Parks et al., 2004, Nature Genetics 36(3): Supplementary Table 1: Deletions generated at Bloomington between trans-heterozygous P element insertions. [FBrf0179070]
Personal communication to FlyBase	Christensen et al., 2007.10.29, Isolation and characterization of Df(2R)BSC400. Isolation and characterization of Df(2R)BSC400. [FBrf0200249] Mason, 2004.11.26, Miniwhite in BSC deletions. Miniwhite in BSC deletions. [FBrf0179886] Deal-Herr and Cook, 2002.7.15, Isolation and Characterization of Df(2R)BSC19. Isolation and Characterization of Df(2R)BSC19. [FBrf0150858]
FlyBase analysis	Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site). Lines in aberration datasets (files on ftp site). [FBrf0219195] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]