Aberration Dmel\Df(2R)BSC29

General Information
Symbol	Dmel\Df(2R)BSC29	Species	D. melanogaster
Name		FlyBase ID	FBab0029979
Feature type	chromosomal_deletion

Computed Breakpoints include
Deleted segment	45D3--45F6
Sequence coordinates
Member of large scale dataset(s)	Dfs_BSC_set1 A set of ~50 targeted deficiencies created by exploiting hybrid element insertion (HEI) and resolution; designed to fill gaps in deletion coverage. (Parks et al., 2004)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{lacW}l(2)k09501^k09501 (Deal-Herr and Cook, 2003.4.2, Parks et al., 2004) P{PZ}l(2)03659⁰³⁶⁵⁹ (Deal-Herr and Cook, 2003.4.2, Parks et al., 2004)
Mutagen	Delta2-3 (Deal-Herr and Cook, 2003.4.2) recombination (Deal-Herr and Cook, 2003.4.2)
Class of aberration (relative to progenitor)	chromosomal_deletion (Deal-Herr and Cook, 2003.4.2, Parks et al., 2004)
Breakpoints	45D3-45D4;45F2-45F6 (Deal-Herr and Cook, 2003.4.2, Parks et al., 2004)
Causes alleles
Carries alleles	bw¹ (Deal-Herr and Cook, 2003.4.2) cn¹ (Deal-Herr and Cook, 2003.4.2)
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	su(rdgA)40 (Georgiev et al., 2012)
Molecular Data
Completely deleted	ced-6 (Georgiev et al., 2012) Pdk (Georgiev et al., 2012) wun2 (Georgiev et al., 2012)
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
	CG13739 (Georgiev et al., 2012) CG13954 (Georgiev et al., 2012) Myd88 (Georgiev et al., 2012)
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Fails to complement Df(2R)BSC279. (Christensen and Cook, 2007.5.8) Fails to complement Df(2R)BSC280. (Christensen and Cook, 2007.5.8) Inferred to overlap with: Df(2R)BSC279. (Christensen and Cook, 2007.5.8) Inferred to overlap with: Df(2R)BSC280. (Christensen and Cook, 2007.5.8)
NOT in combination with other aberrations	The Df(2R)BSC29 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Stocks ( 2 )
Bloomington	6917 Df(2R)BSC29, cn¹ bw¹ sp¹/CyO
Kyoto	130334 Df(2R)BSC29, cn¹ bw¹ sp¹/CyO
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The miniwhite marker from P{lacW}l(2)k09501^k09501 was deleted or disrupted. (Mason, 2004.11.26)
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(2R)BSC29 (Kittel et al., 2006, Kittel et al., 2006, Christensen and Cook, 2007.5.8, Christensen and Cook, 2007.5.8, O'Farrell et al., 2008, Fouquet et al., 2009, Hallermann et al., 2010, Georgiev et al., 2012) DfBSC29 (Owald et al., 2010)
Name Synonym
Secondary FlyBase IDs

References ( 17 )
Research paper	Georgiev et al., 2012, J. Neurogenet. 26(3-4): 338--347 Identification of a suppressor of retinal degeneration in Drosophila photoreceptors. [FBrf0220084] Boerner and Duch, 2010, J. Comp. Neurol. 518(13): 2437--2455 Average shape standard atlas for the adult Drosophila ventral nerve cord. [FBrf0210897] Hallermann et al., 2010, J. Neurosci. 30(43): 14340--14345 Naked dense bodies provoke depression. [FBrf0214096] Owald et al., 2010, J. Cell Biol. 188(4): 565--579 A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila. [FBrf0210057] Fouquet et al., 2009, J. Cell Biol. 186(1): 129--145 Maturation of active zone assembly by Drosophila Bruchpilot. [FBrf0208461] O'Farrell et al., 2008, Dev. Dyn. 237(1): 196--208 Regulation of the Drosophila lin-41 homologue dappled by let-7 reveals conservation of a regulatory mechanism within the LIN-41 subclade. [FBrf0201979] Kittel et al., 2006, Science 312(5776): 1051--1054 Bruchpilot promotes active zone assembly, Ca2+ channel clustering, and vesicle release. [FBrf0190611] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Parks et al., 2004, Nat. Genet. 36(3): 288--292 Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome. [FBrf0175003]
Supplementary material	Kittel et al., 2006, Science 312(5776): Supporting online material for "Bruchpilot promotes active zone assembly, Ca[2+]-channel clustering, and vesicle release". [FBrf0199085] Parks et al., 2004, Nature Genetics 36(3): Supplementary Table 1: Deletions generated at Bloomington between trans-heterozygous P element insertions. [FBrf0179070]
Personal communication to FlyBase	Christensen and Cook, 2007.5.8, Isolation and characterization of Df(2R)BSC279. Isolation and characterization of Df(2R)BSC279. [FBrf0199284] Christensen and Cook, 2007.5.8, Isolation and characterization of Df(2R)BSC280. Isolation and characterization of Df(2R)BSC280. [FBrf0199286] Mason, 2004.11.26, Miniwhite in BSC deletions. Miniwhite in BSC deletions. [FBrf0179886] Deal-Herr and Cook, 2003.4.2, Isolation and Characterization of Df(2R)BSC29. Isolation and Characterization of Df(2R)BSC29. [FBrf0157304]
FlyBase analysis	Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site). Lines in aberration datasets (files on ftp site). [FBrf0219195] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]