FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(1)G1
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General Information
Symbol
Df(1)G1
Species
D. melanogaster
Name
FlyBase ID
FBab0031262
Feature type
Also Known As
Roc1aG1
Computed Breakpoints include
Sequence coordinates
X:644,873..644,873 (Df(1)G1:bk1)
X:654,238..654,238 (Df(1)G1:bk2)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

The X:644873..644873 release 6 coordinate of the left breakpoint corresponds to the insertion site of the P{}CG13367DO46 progenitor reported in FBrf0148948.

The X:654238..654238 release 6 coordinate of the right breakpoint corresponds to the insertion site of the P{EP}Hmt4-20EP1216a progenitor.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (3)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

Df(1)G1 mutant clones in sensory neurons in adult wing do not display any defects in injury-induced axon degeneration (following an axotomy, the severed axons are cleared away normally).

Neoplastic transformation is seen in Df(1)G1 mutant wing disc clones.

Df(1)G1 mutant ddaC neuron clones exhibit severe dendrite pruning defects at 16 hours after pupal formation. No difference is seen at the white prepupal stage.

Df(1)G1 mutant neuroblast clones result in mushroom body γ neurons retain many larval axons at 24 hours after puparium formation that are pruned in wild type. In wandering third instar larvae the dorsal and medial axons are projected normally but the axon branches are less dense than in wild type.

Hemizygous Df(1)G1 males are not viable.

Somatic clones of Df(1)G1 in the wing disc are much smaller and rarer than wild-type controls clones. Those that do form are concentrated close to the anterior wing margin.

Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

Df(1)G1 removes the ORFs of CG13367 and CG13362 as well as that of Roc1a.

Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (8)