Open Close
General Information
Symbol
Df(2L)ED773
Species
D. melanogaster
Name
FlyBase ID
FBab0032524
Feature type
Computed Breakpoints include

[33E9-33E9];[34A3-34A3];

Deleted Segment
Sequence coordinates
2L:12,545,800..12,545,800 (Df(2L)ED773:bk1)
2L:12,975,028..12,975,028 (Df(2L)ED773:bk2)
Member of large scale dataset(s)
Dfs_DrosDel_set1

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.

Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{lacW}bunk00612&P{EP}EP682EP682 and P{lacW}l(2)k07015k07015&P{PZ}l(2)rK639rK639 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{lacW}l(2)k07015k07015&P{PZ}l(2)rK639rK639 and P{lacW}l(2)k11328k11328&P{lacW}l(2)k10105k10105

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations

Many thoracic neuroblasts change to an elongated shape and appear to enter quiescence prematurely. This includes the thoracic neuroblast NB3-3, which generates fewer thoracic EL neurons than in wild type.

NOT in combination with other aberrations

Df(2L)ED773 homozygotes present a significant decrease in the numbers of dividing neuroblasts and dividing neuroblast daughters during stage 14, but not stage 13, of embryogenesis, as compared to controls; these embryos, however, show no significant differences in the number of neuroblasts, as compared to controls.

Precocious entry into quiescence is seen in Df(2L)ED773 mutant NB3-3T neuroblasts.

Mutants display a fully penetrant loss of the eve-positive GMC1 -> RP2/sib lineage.

Mutant embryos have normal U1-U3 neuron fates, but typically lack the U4 and U5 neurons.

Stocks (2)
Notes on Origin
Discoverer
 

Potential deficiency; could be generated as the recombinant product between the reduced derivatives of P{RS5}5-SZ-3100 and P{RS3}CB-0356-3.

Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (6)
References (22)