Aberration Dmel\Df(3L)ED201

General Information
Symbol	Dmel\Df(3L)ED201	Species	D. melanogaster
Name		FlyBase ID	FBab0035323
Feature type	chromosomal_deletion

Computed Breakpoints include	[61B1-61B1];[61C1-61C1];
Deleted segment	61B1--61C1
Map ( GBrowse )	Untitled Document
Sequence coordinates	3L:123,924..123,924 (Df(3L)ED201:bk1) (DrosDel Project, 2007.6.25) 3L:347,941..347,941 (Df(3L)ED201:bk2) (DrosDel Project, 2007.6.25)
Recent Updates
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{RS3r}CB-5349-3 (Ryder, 2003.6.17) P{RS5r}5-SZ-3091 (Ryder, 2003.6.17)
Mutagen	FLPase (Ryder, 2003.6.17)
Class of aberration (relative to progenitor)	chromosomal_deletion (Ryder, 2003.6.17)
Breakpoints	61B1;61C1 (FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions	P{3'.RS5+3.3'}ED201 (Ryder, 2003.6.17)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions. (Ryder and Roote, 2005.11.4) Limits computationally determined from location of progenitor P insertion on genome sequence between P{PZ}trh¹⁰⁵¹² and P{EP}EP3104^EP3104
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Lethal in combination with Df(3L)BSC121. Inferred to overlap with: Df(3L)BSC121. (Andrade and Cook, 2005.8.25)
NOT in combination with other aberrations	Df(3L)ED201 mutants show beta lobe defects that cannot be rescued by expression of Ptpmeg^Scer\UAS.cWa under the control of Scer\GAL4^elav.PLu, suggesting that disruption of some other genes in this deficiency contribute to the beta lobe defects. (Whited et al., 2007)
Stocks ( 2 )
Bloomington	8047 w¹¹¹⁸; Df(3L)ED201, P{3'.RS5+3.3'}ED201/TM6C, cu¹ Sb¹
Kyoto	150377 w¹¹¹⁸; Df(3L)ED201 / TM6C, Sb¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(3L)ED201 (Whited et al., 2007, FlyBase Curators, 2008, Huang et al., 2007)
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	Huang et al., 2007, Development 134(12): 2337--2347 Crk-associated substrate (Cas) signaling protein functions with integrins to specify axon guidance during development. [FBrf0201257] Whited et al., 2007, Development 134(1): 43--53 Ptpmeg is required for the proper establishment and maintenance of axon projections in the central brain of Drosophila. [FBrf0195205]
Personal communication to FlyBase	Andrade and Cook, 2005.8.25, Isolation and characterization of Df(3L)BSC121. Isolation and characterization of Df(3L)BSC121. [FBrf0188668] Ryder and Roote, 2005.11.4, Update from DrosDel Database - Release 4 mappings - November 2005. Update from DrosDel Database - Release 4 mappings - November 2005. [FBrf0188738] Ryder, 2003.6.17, Drosdel deletions. Drosdel deletions. [FBrf0161091]
FlyBase analysis	FlyBase Curators, 2008, Release 5 estimated cytology of aberrations with sequence-defined breakpoints. Release 5 estimated cytology of aberrations with sequence-defined breakpoints. [FBrf0206255] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Computer file	DrosDel Project, 2007.6.25, DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25). DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25). [FBrf0205060]