Aberration Dmel\Df(3L)ED217

General Information
Symbol	Dmel\Df(3L)ED217	Species	D. melanogaster
Name		FlyBase ID	FBab0035331
Feature type	chromosomal_deletion

Computed Breakpoints include	[70F4-70F4];[71E1-71E1];
Deleted segment	70F4--71E1
Map ( GBrowse )	Untitled Document
Sequence coordinates	3L:14,751,170..14,751,170 (Df(3L)ED217:bk1) (DrosDel Project, 2007.6.25) 3L:15,582,196..15,582,196 (Df(3L)ED217:bk2) (DrosDel Project, 2007.6.25)
Member of large scale dataset(s)	Dfs_DrosDel_set1 A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage. (Ryder et al., 2007)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{RS3r}CB-0754-3 (Ryder, 2003.6.17) P{RS5r}5-SZ-3089 (Ryder, 2003.6.17)
Mutagen	FLPase (Ryder, 2003.6.17)
Class of aberration (relative to progenitor)	chromosomal_deletion (Ryder, 2003.6.17)
Breakpoints	70F4;71E1 (FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions	P{3'.RS5+3.3'}ED217 (Ryder, 2003.6.17)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions. (Ryder and Roote, 2005.11.4) Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}Mpcp⁰⁰⁵⁶⁴ and P{PZ}l(3)rO220^rO220 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{EP}Tfb2^EP572 and P{lacW}th^j5C8&P{PZ}Mbs⁰³⁸⁰²
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	DCX-EMAP (Bechstedt et al., 2010)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Inferred to overlap with: Df(3L)BSC558. (Christensen et al., 2008.7.11)
NOT in combination with other aberrations	No cardiac or bristle phenotypes are observed in heterozygous Df(3L)ED217 mutant females. (Casad et al., 2011)
Stocks ( 2 )
Bloomington	8074 w¹¹¹⁸; Df(3L)ED217, P{3'.RS5+3.3'}ED217/TM6C, cu¹ Sb¹
Kyoto	150072 w¹¹¹⁸; Df(3L)ED217 / TM6C, Sb¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(3L)ED217 (Crest et al., 2007, Christensen et al., 2008.7.11, Bardin and Schweisguth, 2006, FlyBase Curators, 2008, Edwards and Mackay, 2009, Bechstedt et al., 2010, Popkova et al., 2012, Casad et al., 2011) ED217 (Shao et al., 2010)
Name Synonym
Secondary FlyBase IDs

References ( 15 )
Research paper	Popkova et al., 2012, PLoS Genet. 8(12): e1003159 Polycomb controls gliogenesis by regulating the transient expression of the gcm/glide fate determinant. [FBrf0220515] Casad et al., 2011, Genetics 189(3): 861--870 Cardiomyopathy Is Associated with Ribosomal Protein Gene Haplo-Insufficiency in Drosophila melanogaster. [FBrf0216591] Bechstedt et al., 2010, Nat. Commun. 1: 11 A doublecortin containing microtubule-associated protein is implicated in mechanotransduction in Drosophila sensory cilia. [FBrf0212106] Shao et al., 2010, PLoS ONE 5(4): e9938 A modifier screen for Bazooka/PAR-3 interacting genes in the Drosophila embryo epithelium. [FBrf0210449] Edwards and Mackay, 2009, Genetics 182(3): 889--897 Quantitative Trait Loci for Aggressive Behavior in Drosophila melanogaster. [FBrf0208371] Crest et al., 2007, Genetics 175(2): 567--584 Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644] Ryder et al., 2007, Genetics 177(1): 615--629 The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource. [FBrf0202170] Bardin and Schweisguth, 2006, Dev. Cell 10(2): 245--255 Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila. [FBrf0190191]
Personal communication to FlyBase	Christensen et al., 2008.7.11, Isolation and characterization of Df(3L)BSC558. Isolation and characterization of Df(3L)BSC558. [FBrf0205003] DrosDel Project, 2007.6.25, DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25). DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25). [FBrf0205060] Ryder and Roote, 2005.11.4, Update from DrosDel Database - Release 4 mappings - November 2005. Update from DrosDel Database - Release 4 mappings - November 2005. [FBrf0188738] Ryder, 2003.6.17, Drosdel deletions. Drosdel deletions. [FBrf0161091]
FlyBase analysis	Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site). Lines in aberration datasets (files on ftp site). [FBrf0219195] FlyBase Curators, 2008, Release 5 estimated cytology of aberrations with sequence-defined breakpoints. Release 5 estimated cytology of aberrations with sequence-defined breakpoints. [FBrf0206255] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]