Aberration Dmel\Df(3L)ED4191

General Information
Symbol	Dmel\Df(3L)ED4191	Species	D. melanogaster
Name		FlyBase ID	FBab0035454
Feature type	chromosomal_deletion

Computed Breakpoints include	[61C3-61C3];[62A2-62A2];
Deleted segment	61C3--62A2
Map ( GBrowse )	Untitled Document
Sequence coordinates	3L:544,273..544,273 (Df(3L)ED4191:bk1) (DrosDel Project, 2007.6.25) 3L:1,478,937..1,478,937 (Df(3L)ED4191:bk2) (DrosDel Project, 2007.6.25)
Recent Updates
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{RS3r}CB-0396-3 (Ryder, 2003.6.17) P{RS5r}5-SZ-3468 (Ryder, 2003.6.17)
Mutagen	FLPase (Ryder, 2003.6.17)
Class of aberration (relative to progenitor)	chromosomal_deletion (Ryder, 2003.6.17)
Breakpoints	61C3;62A2 (FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions	P{3'.RS5+3.3'}ED4191 (Ryder, 2003.6.17)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions. (Ryder and Roote, 2005.11.4) Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{EP}EP3104^EP3104 and P{PZ}l(3)05967⁰⁵⁹⁶⁷ Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{EP}rho^EP3704&P{PZ}l(3)06226⁰⁶²²⁶ and P{PZ}dlt⁰⁴²⁷⁶
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Flies heterozygous for Df(3L)ED4191 display abnormal cardiac chamber sizes. (Yu et al., 2010)
Stocks ( 2 )
Bloomington	8049 w¹¹¹⁸; Df(3L)ED4191, P{3'.RS5+3.3'}ED4191/TM2
Kyoto	150133 w¹¹¹⁸; Df(3L)ED4191 / TM2
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(3L)ED4191 (FlyBase Curators, 2008, Yu et al., 2010)
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Yu et al., 2010, PLoS Genet. 6(5): e1000969 Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila. [FBrf0210954]
Personal communication to FlyBase	Ryder and Roote, 2005.11.4, Update from DrosDel Database - Release 4 mappings - November 2005. Update from DrosDel Database - Release 4 mappings - November 2005. [FBrf0188738] Ryder, 2003.6.17, Drosdel deletions. Drosdel deletions. [FBrf0161091]
FlyBase analysis	FlyBase Curators, 2008, Release 5 estimated cytology of aberrations with sequence-defined breakpoints. Release 5 estimated cytology of aberrations with sequence-defined breakpoints. [FBrf0206255] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Computer file	DrosDel Project, 2007.6.25, DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25). DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25). [FBrf0205060]