FB2025_02 , released April 17, 2025
Aberration: Dmel\Df(3L)ED4470
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General Information
Symbol
Df(3L)ED4470
Species
D. melanogaster
Name
FlyBase ID
FBab0035719
Feature type
chromosomal_deletion
Computed Breakpoints include

[68A6-68A6];[68E1-68E1];

Features within 68A6--68E1
Genomic Maps
Sequence coordinates
3L:11,096,989..11,096,989 (Df(3L)ED4470:bk1)
(DrosDel Project, 2007.6.25)
3L:11,833,230..11,833,230 (Df(3L)ED4470:bk2)
(DrosDel Project, 2007.6.25)
Member of large scale dataset(s)
Dfs_DrosDel_set1

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.

(Ryder et al., 2007)
Nature of Aberration
Cytological Order
Progenitor
P{RS3r}CB-5550-3
(Ryder, 2003.6.17)
P{RS5r}5-SZ-3283
(Ryder, 2003.6.17)
Mutagen
FLPase
(Ryder, 2003.6.17)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Ryder, 2003.6.17)
Breakpoints

68A6;68E1

(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P{3'.RS5+3.3'}ED4470
(Ryder, 2003.6.17)
Formalized genetic data
Genetic mapping information
Comments

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

(Marygold et al., 2007)
Comments on Cytology

Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions.

(Ryder and Roote, 2005.11.4)

Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}l(3)0123901239&P{lacW}l(3)01239j9B4 and P{PZ}CycA02461&P{PZ}CycA03946 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}CycA02461&P{PZ}CycA03946 and P{PZ}rols08232&P{lacW}l(3)j2D3j2D3

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
twy
(Hodge et al., 2021)
Partially deleted / disrupted
Molecular Data
Completely deleted
mRpL2
(Marygold et al., 2007)
RpL10Ab
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (163)
Phenotypic Data
In combination with other aberrations

Inferred to overlap with: Df(3L)BSC379.

(Christensen et al., 2007.10.29)
NOT in combination with other aberrations

No cardiac or bristle phenotypes are observed in heterozygous Df(3L)ED4470 mutant females.

(Casad et al., 2011)

Homozygous stage 16 embryos have elongated and convoluted tracheal dorsal trunks. The embryos also show defects in paracellular diffusion barrier function.

(Nilton et al., 2010)

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)
Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (5)
References (30)