[69C4-69C4];[69F6-69F6];
A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.
69C4;69F6
This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).
Df(3L)ED4486 mutant clones in sensory neurons in adult wing do not display any defects in injury-induced axon degeneration (following an axotomy, the severed axons are cleared away normally).
No cardiac or bristle phenotypes are observed in heterozygous Df(3L)ED4486 mutant females.
The salivary gland distal tip does not initiate turning and migration in embryos homozygous for Df(3L)ED4486 by stage 14.
Df(3L)ED4486 homozygous embryos have defects in head involution, dorsal closure..
Flies heterozygous for the deletion do not show a Minute bristle phenotype.
Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions.
Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}l(3)0508805088 and P{PZ}l(3)0692406924 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{lacW}RpS12s2783 and P{PZ}l(3)0422004220&P{lacW}l(3)j10B6j10B6