Aberration Dmel\Df(3R)ED5142

General Information
Symbol	Dmel\Df(3R)ED5142	Species	D. melanogaster
Name		FlyBase ID	FBab0036381
Feature type	chromosomal_deletion

Computed Breakpoints include	[82B2-82B2];[82F8-82F8];
Deleted segment	82B2--82F8
Map ( GBrowse )	Untitled Document
Sequence coordinates	3R:279,018..279,018 (Df(3R)ED5142:bk1) (DrosDel Project, 2007.6.25) 3R:1,090,605..1,090,605 (Df(3R)ED5142:bk2) (DrosDel Project, 2007.6.25)
Recent Updates
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{RS3r}CB-0212-3 (Ryder and Roote, 2004.11.10) P{RS5r}5-HA-1078 (Ryder and Roote, 2004.11.10)
Mutagen	FLPase (Ryder and Roote, 2004.11.10)
Class of aberration (relative to progenitor)	chromosomal_deletion (Ryder, 2003.6.17, Ryder and Roote, 2004.11.10)
Breakpoints	82B2;82F8 (FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions	P{3'.RS5+3.3'}ED5142 (Ryder and Roote, 2004.11.10)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions. (Ryder and Roote, 2005.11.4) Confirmed by PCR (using the 3-step process described on http://www.drosdel.org.uk/del_confirm.php). (Ryder and Roote, 2004.11.10) Limits computationally determined from location of progenitor P insertion on genome sequence between P{PZ}l(3)02733⁰²⁷³³ and P{EP}EP974
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	corto (Ryder and Roote, 2004.11.10) Karyβ3 (Ryder and Roote, 2004.11.10) opa (Ryder and Roote, 2004.11.10)
Molecular Data
Completely deleted	rtp (Mecklenburg et al., 2010)
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(3R)rtp[1] Df(3R)ED5142 P{Mms19.5.6} flies show a reduced rhabdomere surface area relative to wild type. (Mecklenburg et al., 2010)
NOT in combination with other aberrations
Stocks ( 2 )
Bloomington	9198 w¹¹¹⁸; Df(3R)ED5142, P{3'.RS5+3.3'}ED5142/TM6C, cu¹ Sb¹
Kyoto	150449 w¹¹¹⁸; Df(3R)ED5142 / TM6C, Sb¹
Notes on Origin
Discoverer
	Potential deficiency; could be generated as the recombinant product between the reduced derivatives of P{RS3}CB-0212-3 and P{RS5}5-HA-1078. (Ryder, 2003.6.17)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(3R)5142 (Mecklenburg et al., 2010) Df(3R)ED5142 (FlyBase Curators, 2008)
Name Synonym
Secondary FlyBase IDs

References ( 7 )
Research paper	Mecklenburg et al., 2010, J. Neurosci. 30(4): 1238--1249 Retinophilin is a light-regulated phosphoprotein required to suppress photoreceptor dark noise in Drosophila. [FBrf0209881]
Personal communication to FlyBase	Ryder and Roote, 2005.11.4, Update from DrosDel Database - Release 4 mappings - November 2005. Update from DrosDel Database - Release 4 mappings - November 2005. [FBrf0188738] Ryder and Roote, 2004.11.10, DrosDel deletions confirmed by PCR and genetic tests. DrosDel deletions confirmed by PCR and genetic tests. [FBrf0179888] Ryder, 2003.6.17, Drosdel deletions. Drosdel deletions. [FBrf0161091]
FlyBase analysis	FlyBase Curators, 2008, Release 5 estimated cytology of aberrations with sequence-defined breakpoints. Release 5 estimated cytology of aberrations with sequence-defined breakpoints. [FBrf0206255] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Computer file	DrosDel Project, 2007.6.25, DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25). DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25). [FBrf0205060]