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General Information
Symbol
Df(3R)ED5454
Species
D. melanogaster
Name
FlyBase ID
FBab0036690
Feature type
Computed Breakpoints include

[85E5-85E5];[85F12-85F12];

Deleted Segment
Sequence coordinates
3R:9,726,677..9,726,677 (Df(3R)ED5454:bk1)
3R:10,111,458..10,111,458 (Df(3R)ED5454:bk2)
Member of large scale dataset(s)
Dfs_DrosDel_set1

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.

Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Formalized genetic data
Genetic mapping information
Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

Comments on Cytology

Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions.

Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{EP}CrcEP3006 and P{lacW}s2681 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{EP}Fmr1EP3517&P{PZ}tws02414 and P{PZ}jumu06439&P{lacW}l(3)j8B6j8B6

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

Heterozygous Df(3R)ED5454 mutant females exhibit a dilated cardiomyopathy phenotype, including an increased end-systolic dimension (EDD) and a decreased fractional shortening (FS) compared to controls. Bristles appear short and thin compared to wild type (Minute phenotype).

Flies heterozygous for the deletion show a Minute bristle phenotype.

Stocks (3)
Notes on Origin
Discoverer
 

Potential deficiency; could be generated as the recombinant product between the reduced derivatives of P{RS5}5-SZ-3955 and P{RS3}CB-6098-3.

Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (13)