[85E5-85E5];[85F12-85F12];
A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.
85E5;85F12
This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).
Heterozygous Df(3R)ED5454 mutant females exhibit a dilated cardiomyopathy phenotype, including an increased end-systolic dimension (EDD) and a decreased fractional shortening (FS) compared to controls. Bristles appear short and thin compared to wild type (Minute phenotype).
Flies heterozygous for the deletion show a Minute bristle phenotype.
Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions.
Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{EP}CrcEP3006 and P{lacW}s2681 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{EP}Fmr1EP3517&P{PZ}tws02414 and P{PZ}jumu06439&P{lacW}l(3)j8B6j8B6