A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Aberration Dmel\Df(3R)ED5780

General Information
SymbolDmel\Df(3R)ED5780SpeciesD. melanogaster
NameFlyBase IDFBab0037009
Feature typechromosomal_deletion
Computed Breakpoints include [89E11-89E11];[90C1-90C1];
Deleted segment89E11--90C1
Map ( GBrowse ) GBrowse View Help Untitled Document detailed view
Sequence coordinates
3R:12,882,199..12,882,199 (Df(3R)ED5780:bk1)
(DrosDel Project, 2007.6.25)
3R:13,507,523..13,507,523 (Df(3R)ED5780:bk2)
(DrosDel Project, 2007.6.25)
Member of large scale dataset(s)
A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial core set of 209 isogenic deletions provides ~60% euchromatic genome coverage.
(Ryder et al., 2007)
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Description
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FB2013_03
FB2013_02
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hide Nature of the Aberration
Cytological Order
Progenitor
P{RS3r}CB-5344-3
(Ryder and Roote, 2004.11.10)
P{RS5r}5-HA-1208
(Ryder and Roote, 2004.11.10)
Mutagen
FLPase
(Ryder and Roote, 2004.11.10)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Ryder, 2003.6.17, Ryder and Roote, 2004.11.10)
Breakpoints
89E11;90C1
(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P{3'.RS5+3.3'}ED5780
(Ryder and Roote, 2004.11.10)
Formalized genetic data
Genetic mapping information
Comments
hide Comments on Cytology
Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions.
(Ryder and Roote, 2005.11.4)
Confirmed by PCR (using the 3-step process described on http://www.drosdel.org.uk/del_confirm.php).
(Ryder and Roote, 2004.11.10)
Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{EP}CG5208EP562&P{EP}DadEP3196 and P{PZ}l(3)0788207882 Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{PZ}l(3)0788207882 and P{EP}cpoEP3679
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
ald
(Gilliland et al., 2005)
wheezy
(Ghabrial et al., 2011)
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Dad
(Ryder and Roote, 2004.11.10)
l(3)e02803
(Ryder and Roote, 2004.11.10)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
Stated to complement Sur-8e02803, however Sur-8e02803 is a viable allele. The complementation statement reflects that l(3)e02803e02803, the lethal allele associated with the e02803 chromosome, is not uncovered by Df(3R)ED5780.
(Ryder and Roote, 2004.11.10)
hide Phenotypic Data
In combination with other aberrations
Df(3R)BSC634 failed to complement Df(3R)ED5780 for lethality.
(Christensen et al., 2008.10.20)
Inferred to overlap with: Df(3R)BSC634.
(Christensen et al., 2008.10.20)
Inferred to overlap with: Df(3R)BSC565.
(Cook et al., 2008.7.11)
Df(3R)Exel6176 fails to complement Df(3R)ED5780.
(Cook and Parks, 2006.11.20)
Inferred to overlap with: Df(3R)Exel6176.
(Cook and Parks, 2006.11.20)
Inferred to overlap with: Df(3R)ED5794.
(Ryder and Roote, 2004.11.10)
NOT in combination with other aberrations
No cardiac or bristle phenotypes are observed in heterozygous Df(3R)ED5780 mutant females.
(Casad et al., 2011)
hide Stocks ( 3 )
Bloomington
8104
w1118; Df(3R)ED5780, P{3'.RS5+3.3'}ED5780/TM2
Kyoto
150046
w1118; Df(3R)ED5780/TM3, Ser1
150045
w1118; Df(3R)ED5780/TM2, Ubx130
hide Notes on Origin
Discoverer
Potential deficiency; could be generated as the recombinant product between the reduced derivatives of P{RS5}5-HA-1208 and P{RS3}CB-5344-3.
(Ryder, 2003.6.17)
hide Balancer / Genotype Variants of the Aberration
hide Separable Components
hide Other Comments
hide Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym
Df(3R)5780
(Pilot et al., 2006)
Df(3R)ED5780
(Cook and Parks, 2006.11.20, Cook et al., 2008.7.11, Christensen et al., 2008.10.20, FlyBase Curators, 2008, Casad et al., 2011, Ghabrial et al., 2011)
ED5780
(Shao et al., 2010)
Name Synonym
Secondary FlyBase IDs
hide References ( 16 )
Research paper
Casad et al., 2011, Genetics 189(3): 861--870
Cardiomyopathy Is Associated with Ribosomal Protein Gene Haplo-Insufficiency in Drosophila melanogaster. [FBrf0216591]
Ghabrial et al., 2011, PLoS Genet. 7(7): e1002087
A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. [FBrf0214368]
Shao et al., 2010, PLoS ONE 5(4): e9938
A modifier screen for Bazooka/PAR-3 interacting genes in the Drosophila embryo epithelium. [FBrf0210449]
Ryder et al., 2007, Genetics 177(1): 615--629
The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource. [FBrf0202170]
Pilot et al., 2006, Development 133(4): 711--723
Developmental control of nuclear morphogenesis and anchoring by charleston, identified in a functional genomic screen of Drosophila cellularisation. [FBrf0190315]
Gilliland et al., 2005, Curr. Biol. 15(7): 672--677
The meiotic defects of mutants in the Drosophila mps1 gene reveal a critical role of Mps1 in the segregation of achiasmate homologs. [FBrf0187308]
Personal communication to FlyBase
Christensen et al., 2008.10.20, Isolation and characterization of Df(3R)BSC634.
Isolation and characterization of Df(3R)BSC634. [FBrf0206112]
Cook et al., 2008.7.11, Isolation and characterization of Df(3R)BSC565.
Isolation and characterization of Df(3R)BSC565. [FBrf0205017]
DrosDel Project, 2007.6.25, DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25).
DrosDel deletion data mapped to Release 5.1 (updated 2007-06-25). [FBrf0205060]
Cook and Parks, 2006.11.20, Notes on P{XP}d06981 and Df(3R)Exel6176.
Notes on P{XP}d06981 and Df(3R)Exel6176. [FBrf0198638]
Ryder and Roote, 2005.11.4, Update from DrosDel Database - Release 4 mappings - November 2005.
Update from DrosDel Database - Release 4 mappings - November 2005. [FBrf0188738]
Ryder and Roote, 2004.11.10, DrosDel deletions confirmed by PCR and genetic tests.
DrosDel deletions confirmed by PCR and genetic tests. [FBrf0179888]
Ryder, 2003.6.17, Drosdel deletions.
Drosdel deletions. [FBrf0161091]
FlyBase analysis
Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site).
Lines in aberration datasets (files on ftp site). [FBrf0219195]
FlyBase Curators, 2008, Release 5 estimated cytology of aberrations with sequence-defined breakpoints.
Release 5 estimated cytology of aberrations with sequence-defined breakpoints. [FBrf0206255]
FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type.
En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]