Aberration Dmel\Df(2R)247

General Information
Symbol	Dmel\Df(2R)247	Species	D. melanogaster
Name		FlyBase ID	FBab0037638
Feature type	chromosomal_deletion

Computed Breakpoints include
Sequence coordinates
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{SUPor-P}KG01086 (Myster and Peifer, 2003.9.11, Myster et al., 2004)
Mutagen	P-element activity (Myster and Peifer, 2003.9.11, Myster et al., 2004)
Class of aberration (relative to progenitor)	chromosomal_deletion (Myster and Peifer, 2003.9.11)
Breakpoints	[];[] (Myster and Peifer, 2003.9.11, Myster et al., 2004)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments	FlyBase Curator comment: eIF-4B is stated to be the next gene proximal to CG42595 in FlyBase GBrowse (Release 5.29) and is therefore predicted to be deleted by Df(2R)247. The fact that this isn't the case is consistent with eIF-4B being incorrectly located to 2Rh in FlyBase - it's actually in 3Lh (see data on the CP000217 scaffold in FBrf0200204). (Coulthard and Alm, 2010.7.21)
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	CG17683 (Myster and Peifer, 2003.9.11, Myster et al., 2004, Coulthard et al., 2010) CG40127 (Myster et al., 2004, Myster and Peifer, 2003.9.11, Coulthard et al., 2010) IntS3 (Myster et al., 2004, Marygold et al., 2005, Myster and Peifer, 2003.9.11, Coulthard et al., 2010) l(2)NC133 (Myster and Peifer, 2003.9.11, Myster et al., 2004) l(2)NC204 (Myster and Peifer, 2003.9.11, Myster et al., 2004, Marygold et al., 2005) p120ctn (Myster et al., 2004) RpL38 (Myster and Peifer, 2003.9.11, Myster et al., 2004, Marygold et al., 2005, Coulthard et al., 2010) Stlk (Myster et al., 2004) uex (Marygold et al., 2005, Myster et al., 2004, Myster and Peifer, 2003.9.11, Coulthard et al., 2010)
Molecular Data
Completely deleted	CG17683 (Coulthard et al., 2010) CG40085 (Coulthard et al., 2010) CG40127 (Coulthard et al., 2010) CG40131 (Coulthard et al., 2010) CG40133 (Coulthard et al., 2010) CG40270 (Coulthard et al., 2010) CG41322 (Coulthard et al., 2010) CG41323 (Coulthard et al., 2010) CG41363 (Coulthard et al., 2010) CG41449 (Coulthard et al., 2010) Gprk1 (Coulthard et al., 2010) Haspin (Coulthard et al., 2010) IntS3 (Coulthard et al., 2010) p120ctn (Myster et al., 2004) RYamide (Coulthard et al., 2010) Stlk (Myster et al., 2004) uex (Coulthard et al., 2010)
Genes NOT Deleted / Disrupted
Complementation Data
	BubR1 (Myster et al., 2004) CG17486 (Myster et al., 2004) IntS3 (Myster et al., 2004) l(2)309 (Myster et al., 2004) l(2)NC12 (Myster et al., 2004) l(2)NC14 (Myster et al., 2004) l(2)NC30 (Myster et al., 2004) l(2)NC45 (Myster et al., 2004) l(2)NC47 (Myster et al., 2004) l(2)NC83 (Myster et al., 2004) l(2)NC85 (Myster et al., 2004) l(2)NC114 (Myster et al., 2004) l(2)NC136 (Myster et al., 2004) l(2)NC139 (Myster et al., 2004) l(2)NC148 (Myster et al., 2004) l(2)NC192 (Myster et al., 2004) Nipped-A (Myster et al., 2004) Nipped-B (Myster et al., 2004) sxc (Myster et al., 2004) vlc (Myster et al., 2004)
Molecular Data
	CG17883 (Coulthard et al., 2010) CG41311 (Coulthard and Alm, 2010.7.21) CG41592 (Coulthard et al., 2010) eIF-4B (Coulthard and Alm, 2010.7.21)
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 1 )
Bloomington	7155 w^*; Df(2R)247/CyO, P{GAL4-Kr.C}DC3, P{UAS-GFP.S65T}DC7
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Deletes the Stlk and p120ctn sequences. (Myster and Peifer, 2003.9.11)
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	247 (Coulthard et al., 2010) Df(2R)247 (Coulthard and Alm, 2010.7.21, Coulthard et al., 2010) Df(2R) 247 (Coulthard et al., 2010)
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Coulthard et al., 2010, Genetics 185(2): 479--495 Essential loci in centromeric heterochromatin of Drosophila melanogaster. I: the right arm of chromosome 2. [FBrf0211235] Marygold et al., 2005, Genetics 169(2): 683--695 Genetic analysis of RpL38 and RpL5, two Minute genes located in the centric heterochromatin of chromosome 2 of Drosophila melanogaster. [FBrf0187649] Myster et al., 2004, Genetics 166(2): 807--822 Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: a window on the heterochromatin-euchromatin junction. [FBrf0174713]
Personal communication to FlyBase	Coulthard and Alm, 2010.7.21, eIF-4B and CG41311 mis-mapped in FlyBase. eIF-4B and CG41311 mis-mapped in FlyBase. [FBrf0211310] Myster and Peifer, 2003.9.11, Myster and Peifer lethals. Myster and Peifer lethals. [FBrf0161610]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]