Aberration Dmel\Df(2R)Exel8056

General Information
Symbol	Dmel\Df(2R)Exel8056	Species	D. melanogaster
Name		FlyBase ID	FBab0037971
Feature type	chromosomal_deletion
Also Known As	Df(2L)Exel8056

Computed Breakpoints include	[49C2-49C2];[49E1-49E1];
Deleted segment	49C2--49E1
Map ( GBrowse )	Untitled Document
Sequence coordinates	2R:8,630,644..8,630,724 (Df(2R)Exel8056:bk1) (Bloomington Drosophila Stock Center, 2008.8.7) 2R:8,781,610..8,781,621 (Df(2R)Exel8056:bk2) (Bloomington Drosophila Stock Center, 2008.8.7)
Member of large scale dataset(s)	Dfs_Exelixis_set1 A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage. The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003: a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication. (Parks et al., 2004, Cook, 2012.9.12)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	P{XP}d09955 (Parks et al., 2004, Parks, 2004.9.23) PBac{WH}vg^f02736 (Parks et al., 2004, Parks, 2004.9.23)
Mutagen	FLPase (Parks et al., 2004, Parks, 2004.9.23)
Class of aberration (relative to progenitor)	chromosomal_deletion (Parks et al., 2004, Parks, 2004.9.23)
Breakpoints	49C2;49E1 (FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions	P+PBac{XP5.WH5}Exel8056 (Parks, 2004.9.23, Parks et al., 2004)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 computationally determined from location of progenitor P insertion on genome sequence between P{EP}Amph^EP2175/P{lacW}spt4^k05316 and P{PZ}ox¹ Limits of break 2 computationally determined from location of progenitor P insertion on genome sequence between P{lacW}bic^k10712 and P{PZ}l(2)01424⁰¹⁴²⁴
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments
	Predicted to delete CG7115, Rack1, mts, CG14537, CG14535, lectin-28C, CG14534, Proct, tRNA:G3:28D, Spz3, CG7102, CG18591, CG31902, CG31902, CG33121, CG7093 and CG14532, however this was when Exelixis had published coordinates of insertions P{XP}d09955 and PBac{WH}vg^f02736 as being on 2L, not 2R. See Parks, 2004.9.23, personal communication to FlyBase, for explanation. (Ryder, 2004.4.26)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygotes show hypersensitivity to halothane compared to controls. (Alone et al., 2009)
Stocks ( 1 )
Bloomington	7916 w¹¹¹⁸; Df(2R)Exel8056/CyO
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(2L)Exel8056 (Ryder, 2004.4.26, Parks et al., 2004, ) Df(2R)Exel8056 (FlyBase Curators, 2008, Cook, 2012.9.12) Exel8056 (Alone et al., 2009)
Name Synonym
Secondary FlyBase IDs

References ( 10 )
Research paper	Alone et al., 2009, Anesthesiology 111(1): 15--24 Impact of gene copy number variation on anesthesia in Drosophila melanogaster. [FBrf0208265] Parks et al., 2004, Nat. Genet. 36(3): 288--292 Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome. [FBrf0175003]
Supplementary material	Parks et al., 2004, Nature Genetics 36(3): Supplementary Table 2. [FBrf0174230]
Personal communication to FlyBase	Cook, 2012.9.12, Notes on the Exelixis deletion collection. Notes on the Exelixis deletion collection. [FBrf0219608] Bloomington Drosophila Stock Center, 2008.8.7, Release 5 sequence coordinates of Exelixis deficiencies. Release 5 sequence coordinates of Exelixis deficiencies. [FBrf0205061] Parks, 2004.9.23, More Exelixis deficiencies. More Exelixis deficiencies. [FBrf0179868] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site). Lines in aberration datasets (files on ftp site). [FBrf0219195] FlyBase Curators, 2008, Release 5 estimated cytology of aberrations with sequence-defined breakpoints. Release 5 estimated cytology of aberrations with sequence-defined breakpoints. [FBrf0206255] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]