A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.
The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.
Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.
The head skeleton is not fully internalised in homozygous larvae and is poorly differentiated. Ventral denticles are hardly discernible. The overall architecture of the cuticle is normal in homozygous larvae, and the chitinous procuticle has a wild-type texture and thickness. Homozygous larvae derived from homozygous female germline clones show the same phenotype as zygotically mutant homozygous larvae.