A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.
The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.
Breakpoint based on release 3 sequence coordinate from Parks et al., 2004 (FBrf0174230), converted to release 5 coordinate.
Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.
This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).
The microtubule and centrosomal abnormalities (irregular number of centrosomes and spindle defects, including loss of astral microtubules) observed in brain neuroblasts in Pfdn2Δ10 single mutant and mgrG5308/Df(3R)Exel6160 third instar larvae are exacerbated further in Pfdn2Δ10,mgrG5308 double mutants.
Flies heterozygous for the deletion do not show a Minute bristle phenotype.