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General Information
D. melanogaster
FlyBase ID
Feature type
Computed Breakpoints include


Deleted Segment
Sequence coordinates
3R:23,385,178..23,385,178 (Df(3R)Exel6194:bk1)
3R:23,641,406..23,641,406 (Df(3R)Exel6194:bk2)
Member of large scale dataset(s)

A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.

The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.

Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information

Breakpoint based on release 3 sequence coordinate from Parks et al., 2004 (FBrf0174230), converted to release 5 coordinate.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Phenotypic Data
In combination with other aberrations

The amount of apoptosis seen in Df(3R)Exel6194/Df(3R)irk2B mutant wing discs is similar to wild type.

The wings from Df(3R)Exel6194/Df(3R)irk2B mutant flies show wing vein defects, including incomplete or branched posterior cross veins, incomplete L5 vein, bifurcations of L3 and L4 veins and wing bristle transformations. 39% of flies have held-out wings from hinge defects. Rare Df(3R)Exel6194/Df(3R)irk2B mutant wings are notched or smaller than wild type. The penetrance and severity of wing phenotypes are dependent both on sex and the temperature during development; the most severe phenotypes are seen in males raised at low temperatures, with 38% of male flies having wing defects at 25[o]C.

NOT in combination with other aberrations

17% of heterozygous Df(3R)Exel6194 mutant males display wing vein defects.

Stocks (1)
Notes on Origin
Balancer / Genotype Variants of the Aberration
Separable Components
Other Comments
Synonyms and Secondary IDs (5)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (11)