A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.
The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.
Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.
Df(3R)Exel6216 embryos that are at stage 15 or above show defects in the apical surfaces of the secretory cells. These embryos also show gross irregularities in the salivary gland lumena; the lumena have regions of expansion and constriction, as well as regions where the tubes appear closed. Cell polarity and other aspects of gland morphology are not affected.