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General Information
D. melanogaster
FlyBase ID
Also Known As
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information

A 5kb tandem duplication is uniquely associated with all RanGapSD chromosomes.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations
    Stocks (8)
    Notes on Origin

    Analysis of different SD chromosomes containing the Dp(2;2)RanGapSD duplication suggests that the duplication arose only once; all SD chromosomes (9 independently isolated chromosomes have been tested) have the same constellation of polymorphic restriction sites in a 50kb region that extends 20kb distal and 28kb proximal to the duplication, and have one of two conserved haplotypes in the region that is 28-43kb proximal to the duplication. Two different SD chromosomes, SD-Roma and SD-VO17, both lack the pericentric and/or 2R inversions that are typically associated with SD chromosomes and were isolated from Mediterranean populations. If the duplication arose only once, it may have originated in the Mediterranean region on a chromosome that was free of inversions. The specific inversions associated with the different SD chromosomes would then have arisen subsequently after the geographic spread of these chromosomes.

    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments
    Synonyms and Secondary IDs (5)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (34)