|Computed Breakpoints include|
|Member of large scale dataset(s)|
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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This section does not currently display links that were removed or gene model changes.
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|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
|Formalized genetic data|
|Genetic mapping information|
|Comments on Cytology|
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
Lethal in combination with Df(2L)FCK-20. Df(2L)FCK-20/Df(2L)k07716-V.1 animals die at the pupal stage and no adult escapers are seen. The mutant pharate adults have rough eyes, scalloped wings and bristles are shorter than normal or missing. Wings discs of mutant third instar larvae show high levels of apoptosis compared to control discs. Mitotic neuroblasts from Df(2L)FCK-20/Df(2L)k07716-V.1 larval brains show a high frequency of telomere fusions and chromosome breaks. Single telomeric associations (in which a single telomere fuses with either its sister telomere or a single non-sister telomere) and double telomere associations are seen. Metaphases with rearranged chromosomes and hyperploid/polyploid cells are seen. Chromosome breaks involving either one or both sister chromatids are seen. Df(2L)FCK-20/Df(2L)k07716-V.1 mutant cells are at least one order of magnitude more sensitive than wild-type cells to the induction of chromosome breaks by irradiation.
|NOT in combination with other aberrations|
|Stocks ( 0 )|
|Notes on Origin|
|Balancer / Genotype Variants of the Aberration|
|Synonyms & Secondary IDs ( 2 )|
|Secondary FlyBase IDs|
|References ( 3 )|