FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2R)BSC134
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General Information
Symbol
Df(2R)BSC134
Species
D. melanogaster
Name
FlyBase ID
FBab0044840
Feature type
chromosomal_deletion
Computed Breakpoints include

[50E1-50E1];[50E6-50E6];

Features within 50E1--50E6
Genomic Maps
Sequence coordinates
2R:14,176,098..14,176,098 (Df(2R)BSC134:bk1)
(Bloomington Drosophila Stock Center, 2008.8.7)
2R:14,265,801..14,265,801 (Df(2R)BSC134:bk2)
(Bloomington Drosophila Stock Center, 2008.8.7)
Member of large scale dataset(s)
Dfs_BSC_set2

A set of ~800 largely isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Designed to fill gaps in deletion coverage and breakpoint placement; also used to replace older available deficiencies that have not been molecularly mapped.

(Cook et al., 2012)
Nature of Aberration
Cytological Order
Progenitor
PBac{WH}cgf03211
(Christensen and Cook, 2006.3.8)
P{XP}CG8547d05392
(Christensen and Cook, 2006.3.8)
Mutagen
FLPase
(Christensen and Cook, 2006.3.8)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Christensen and Cook, 2006.3.8)
Breakpoints

50E1;50E6

(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P+PBac{XP5.WH5}BSC134
(Christensen and Cook, 2006.3.8)
Formalized genetic data
Genetic mapping information
Comments

Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.

(Bloomington Drosophila Stock Center, 2008.8.7)

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)
Comments on Cytology

Cytological breakpoints of Df(2R)BSC134 predicted from the transposable element insertions sites using release 4 coordinates are 50E1;50E6.

(Christensen and Cook, 2006.3.8)
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Hsc70-5
(Christensen and Cook, 2006.3.8)
RpS23
(Christensen and Cook, 2006.3.8)
Sox15
(Christensen and Cook, 2006.3.8)
Partially deleted / disrupted
Molecular Data
Completely deleted
RpS23
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (17)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

Flies heterozygous for the deletion show a Minute bristle phenotype.

(Marygold et al., 2007)

Df(2R)BSC134 heterozygotes show a severe Minute phenotype from deletion of the haploinsufficient RpS23 gene.

(Christensen and Cook, 2006.3.8)
Stocks (1)
Notes on Origin
Discoverer
 

The stock contains a second-site deletion uncovering l(2)gl.

(Roegiers et al., 2009)
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

Presence of P+PBac{XP5.WH5}BSC134 was verified using the PCR methods and primers described in FBrf0175003.

(Christensen and Cook, 2006.3.8)
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Df(2R)BSC134
(Clough et al., 2014, Cook et al., 2012, Roegiers et al., 2009, FlyBase Curators, 2008)
Df(2R)FDD-0312160
(Cook and Ryder, 2007.5.14)
Name Synonyms
Secondary FlyBase IDs
    References (11)