Aberration Dmel\Df(3L)Gr64^ab

General Information
Symbol	Dmel\Df(3L)Gr64^ab	Species	D. melanogaster
Name		FlyBase ID	FBab0045247
Feature type	chromosomal_deletion

Computed Breakpoints include
Deleted segment	64A4--64A4 (Estimated cytology)
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{EP}Gr64a^GE24923 (Jiao et al., 2007)
Mutagen	Delta2-3 (Jiao et al., 2007)
Class of aberration (relative to progenitor)	chromosomal_deletion (Jiao et al., 2007)
Breakpoints
Causes alleles	Gr64b^ab (Jiao et al., 2007)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments	Imprecise excision of the progenitor insertion, resulting in a 3.1kb deletion which removes the entire Gr64a gene and removes 868bp at the 5' end of Gr64b. (Jiao et al., 2007)
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Gr64a (Jiao et al., 2007)
Molecular Data
Completely deleted	Gr64a (Jiao et al., 2007)
Partially deleted	Gr64b (Jiao et al., 2007)
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
	CG11594 (Jiao et al., 2007)
Genes Duplicated
Complementation Data
Partially duplicated	CG11594 (Jiao et al., 2007)
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Df(3L)Gr64^ab flies prefer fructose to sucrose, whereas wild-type flies prefer sucrose. In addition Df(3L)Gr64^ab flies fail to show a bias in favor of the 5mM over 1mM sucrose, but retain the ability to select the 5mM over 2mM fructose. Thus, the behavioral response to sucrose, but not fructose, is defective in Df(3L)Gr64^ab flies. Df(3L)Gr64^ab flies exhibit a normal preference for 20mM arabinose over 2mM fructose. However, unlike wild-type, the Df(3L)Gr64^ab mutant prefers fructose over either glucose or maltose. Also in contrast to wildtype, Df(3L)Gr64^ab selects fructose rather than trehalose, which is surprising given that trehalose is the ligand that activates Gr5a[01]. Df(3L)Gr64^ab flies show a normal aversion to quinine and caffeine. The frequencies of action potentials induced by sucrose, glucose, maltose, and trehalose are dramatically reduced in Df(3L)Gr64^ab flies. (Jiao et al., 2007)
Stocks ( 1 )
Bloomington	24894 Df(3L)Gr64^ab
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(3L)Gr64^ab (FlyBase, 2007, ) Gr64^ab (Jiao et al., 2007)
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Jiao et al., 2007, Proc. Natl. Acad. Sci. U.S.A. 104(35): 14110--14115 A Drosophila gustatory receptor required for the responses to sucrose, glucose, and maltose identified by mRNA tagging. [FBrf0200681]
FlyBase analysis	FlyBase Curators, 2008, Estimated deleted and duplicated segments carried by aberration chromosomes. Estimated deleted and duplicated segments carried by aberration chromosomes. [FBrf0206134] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]

Aberration Dmel\Df(3L)Gr64ab

Aberration Dmel\Df(3L)Gr64^ab