Aberration Dmel\Dp(1;Y)BSC50

General Information
Symbol	Dmel\Dp(1;Y)BSC50	Species	D. melanogaster
Name		FlyBase ID	FBab0046160
Feature type	interchromosomal_duplication

Computed Breakpoints include
Duplicated segment	1Lt--1B5 (Estimated cytology) X:10B13--10C5--11A1 (Estimated cytology) 20F3--h28--h28--h29 (Estimated cytology)
Map ( GBrowse )	Untitled Document
Sequence coordinates	X:1..1 (Dp(1;Y)BSC50:bk1) (Cook et al., 2010.2.9) X:387,562..387,562 (Dp(1;Y)BSC50:bk2) (Cook et al., 2010.2.9) X:11,347,096..11,451,050 (Dp(1;Y)BSC50:bk3) (Cook et al., 2010.2.9) X:11,901,120..11,901,120 (Dp(1;Y)BSC50:bk4) (Cook et al., 2010.2.9)
Member of large scale dataset(s)	Dps(X)BSC_set1 Series of Dp(1;Y) stocks carrying segments of the X chromosome on the tip of Y chromosome; in an isogenic background. At the time of publication (FBrf0212582), the Dp(1;Y) collection provided a minimum of 78% coverage with duplication breakpoints spaced a median of nine genes apart. After generating all the Dp(1;Y)BSC chromosomes as described in FBrf0212582, we calculated the minimal euchromatic coverage of the X chromosome provided by these duplications as 97.0%. (Cook et al., 2010, Cook, 2012.8.8)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	In(1)BSC13 (Cook et al., 2010.2.9)
Mutagen	137Cs gamma ray (Cook et al., 2010.2.9)
Class of aberration (relative to progenitor)	chromosomal_deletion (Cook et al., 2010.2.9)
Breakpoints
Causes alleles
Carries alleles	B^S (Cook et al., 2010.2.9)
Transposon Insertions	P{3'.RS5+3.3'}BSC13 (Cook et al., 2010.2.9)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	Dp(1;Y)BSC50 carries five regions from the X chromosome. Three segments are appended to YS: a distal X segment (1Lt;1B5, X:1Lt;387562 (R5)), a medial X segment (10B13-10C5;11A1, X:11347096..11451050;11901120) and a basal X segment that extends distally from a point in centric heterochromatin distal to bb to a point either in X heterochromatin or in basal euchromatin. An X segment extending proximal from a point between fog and stnA (X:22228492..22384175) to an unknown point in X heterochromatin and a small X segment from 16A carrying B[S] are appended to YL. (Cook et al., 2010.2.9) Dp(1;Y)BSC50 was generated from C(1;Y)N12, In(1)BSC13 by a large deletion. The proximal deletion breakpoint fell between X:22366703 (20F3, Release 5) and h28--h29. Consequently, no basal euchromatic genes distal to stnA are present on Dp(1;Y)BSC50. (Cook et al., 2010.10.12)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated	dy (Cook et al., 2010) m (Cook et al., 2010)
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 1 )
Bloomington	29774 Dp(1;Y)BSC50, y⁺ P{3'.RS5+3.3'}BSC13, B^S/Df(1)ED7147, w¹¹¹⁸ P{3'.RS5+3.3'}ED7147/C(1)RA, In(1)sc^J1, In(1)sc⁸, l(1)1Ac¹, sc^J1 sc⁸
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	50 (Cook et al., 2010) Dp(1;Y)BSC50 (Cook et al., 2010.2.9, Cook et al., 2010.10.12, Cook et al., 2010)
Name Synonym	Dp(1;Y)BSC50 (Cook et al., 2010.10.12)
Secondary FlyBase IDs

References ( 6 )
Research paper	Cook et al., 2010, Genetics 186(4): 1095--1109 A new resource for characterizing X-linked genes in Drosophila melanogaster: systematic coverage and subdivision of the X chromosome with nested, Y-linked duplications. [FBrf0212582]
Supplementary material	Cook et al., 2010, Genetics 186(4): Table S3. Extents of duplicated medial segments in Dp(1;Y)s. [FBrf0219067]
Personal communication to FlyBase	Cook, 2012.8.8, Duplication coverage of X euchromatin provided by Dp(1;Y)BSC chromosomes. Duplication coverage of X euchromatin provided by Dp(1;Y)BSC chromosomes. [FBrf0219194] Cook et al., 2010.2.9, Generating Y-linked X chromosome duplications for region 10B to 11A. Generating Y-linked X chromosome duplications for region 10B to 11A. [FBrf0209982] Cook et al., 2010.10.12, Basal X chromosome segments present on Dp(1;Y)BSC chromosomes. Basal X chromosome segments present on Dp(1;Y)BSC chromosomes. [FBrf0212099]
FlyBase analysis	Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site). Lines in aberration datasets (files on ftp site). [FBrf0219195]