Aberration Dmel\Df(2L)ush^E6

General Information
Symbol	Dmel\Df(2L)ush^E6	Species	D. melanogaster
Name		FlyBase ID	FBab0046551
Feature type	chromosomal_deletion
Also Known As	ush^E6

Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	ethyl methanesulfonate (Biryukova and Heitzler, 2008, Heitzler, 2010.5.12)
Class of aberration (relative to progenitor)	chromosomal_deletion (Biryukova and Heitzler, 2008, Heitzler, 2010.5.12)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments	The size of this deletion is around 70kb. (Heitzler, 2010.5.12)
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	ec (Heitzler, 2010.5.12)
Molecular Data
Completely deleted	ec (Heitzler, 2010.5.12)
Genes NOT Deleted / Disrupted
Complementation Data
	ex (Heitzler, 2010.5.12)
Molecular Data
	ex (Heitzler, 2010.5.12)
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Homozygous embryos are U-shaped. (Biryukova and Heitzler, 2008) Homozygous clones in the lateral part of the notum differentiate normally. Clones that extend into the scutellum fail to differentiate, producing large gaps in this region. Clones touching the dorsal midline are associated with a cleft in the thorax, and clones extending into the dorsocentral area are associated with a lack or mis-positioning of the dorsocentral bristles. Dorsocentral bristles produced by wild-type cells in flies with clones in part of the dorsocentral area are also misplaced from their normal positions. (Cubadda et al., 1997)
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(2L)ush^E6 (Heitzler, 2010.5.12, Biryukova and Heitzler, 2008) ush^E6 (Heitzler, 2010.5.12, Cubadda et al., 1997)
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Biryukova and Heitzler, 2008, Dev. Biol. 323(1): 64--75 Drosophila C-terminal binding protein, dCtBP is required for sensory organ prepattern and sharpens proneural transcriptional activity of the GATA factor Pnr. [FBrf0207210] Cubadda et al., 1997, Genes Dev. 11(22): 3083--3095 u-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in Drosophila. [FBrf0099172]
Personal communication to FlyBase	Heitzler, 2010.5.12, ush[E6] = Df(2L)ush[E6] ush[E6] = Df(2L)ush[E6] [FBrf0210807]

Aberration Dmel\Df(2L)ushE6

Aberration Dmel\Df(2L)ush^E6