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General Information
Symbol
Df(3R)ΔmiRNA
Species
D. melanogaster
Name
FlyBase ID
FBab0046732
Feature type
Also Known As
ΔmiRNA
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Gene conversion using P{ΔmiRNA.donor} as the donor. The gene conversion event has resulted in most of the genomic sequence that encodes both the mir-iab-4 and mir-iab-8 microRNAs (these microRNAs are encoded on opposite strands) being replaced with sequence encoding the HindIII and I-SceI restriction enzyme sites.

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations

Female fertile and male sterile in transheterozygous combination with T(2;3)iab445.

Male and female fertile in transheterozygous combination with In(3LR)iab333, Ab(?;3)iab3B1, In(3R)iab9Uab1, Tp(3;Y)Abd-BS10, T(2;3)iab965, Ab(?;3)iab386A or T(2;3;4)iab4302.

Male and female sterile in transheterozygous combination with T(2;3)iab6105, In(3R)iab6G, In(3R)iab7SGA, In(3R)iab7Spth, Tp(3;2)iab5843 or Ab(?;3)iab-4186.

Weakly fertile transheterozygous combination with Ab(?;3)iab42330.

NOT in combination with other aberrations

Homozygotes show partial lethality. Some lethality is seen during the embryonic stage and some during the pupal stage.

Homozygous males show a significant decrease in median lifespan compared to controls.

Homozygous males and females are sterile.

Homozygous adults show no evidence of segmental transformation in the abdominal cuticle of either sex. Homozygous adults of both sexes are sterile. Females have ovaries with eggs of normal size, but only very rare individuals ever lay an egg, even after mating with wild-type males, and these eggs never hatch. Males have morphologically normal testes containing motile sperm. Homozygous females mate with wild-type males as readily as do heterozygous sibling females. Homozygous males show normal courtship except that they never complete copulation. They mount the females, but do not bend their abdomens quite far enough to mate.

Stocks (0)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (6)