Aberration Dmel\Df(3L)ΔGr64

General Information
Symbol	Dmel\Df(3L)ΔGr64	Species	D. melanogaster
Name		FlyBase ID	FBab0047080
Feature type	chromosomal_deletion
Also Known As	ΔGr64

Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{XP}CG11593^d06001 (Slone et al., 2007) PBac{WH}f03449 (Slone et al., 2007)
Mutagen	FLPase (Slone et al., 2007)
Class of aberration (relative to progenitor)	chromosomal_deletion (Slone et al., 2007)
Breakpoints
Causes alleles	Rcd5^ΔGr64 (Slone et al., 2007)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Partially deleted	Rcd5 (Slone et al., 2007)
Completely deleted	CG11593 (Slone et al., 2007) CG11594 (Slone et al., 2007) fd64A (Slone et al., 2007) Gr64a (Slone et al., 2007) Gr64b (Slone et al., 2007) Gr64c (Slone et al., 2007) Gr64d (Slone et al., 2007) Gr64e (Slone et al., 2007) Gr64f (Slone et al., 2007) Mul1 (Slone et al., 2007)
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	When given a choice between trehalose and fructose, wild-type flies strongly prefer trehalose. In contrast, Df(3L)ΔGr64 mutant flies favor fructose. Df(3L)ΔGr64 mutants lack behavioural and electrophysiological responses to sucrose, maltose and glucose. In contrast to wild-type flies, virtually no action potentials are produced upon presentation of trehalose in Df(3L)ΔGr64 mutants. (Jiao et al., 2008) Df(3L)ΔGr64 is homozygous lethal. P{t15.3.R1}/+, P{UAS-Rescue.R2}/+, Df(3L)ΔGr64/Df(3L)ΔGr64 flies show a drastic reduction in proboscis extension reflex for sucrose, glucose, trehalose, arabinose, and maltose. The introduction of P{UAS_Gr64abcdf.GFP} into this genetic background rescues the sugar-response phenotype. Homozygous Df(3L)ΔGr64 mutant flies show as robust a response to fructose as do wild-type flies. Homozygous Df(3L)ΔGr64 mutant flies show similar responses to bitter compounds as do wild-type flies. (Slone et al., 2007)
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(3L)ΔGr64 ΔGr64 (Slone et al., 2007, Jiao et al., 2008)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Jiao et al., 2008, Curr. Biol. 18(22): 1797--1801 Gr64f is required in combination with other gustatory receptors for sugar detection in Drosophila. [FBrf0206328] Slone et al., 2007, Curr. Biol. 17(20): 1809--1816 Sugar receptors in Drosophila. [FBrf0200736]