FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(3L)ΔGr64
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General Information
Symbol
Df(3L)ΔGr64
Species
D. melanogaster
Name
FlyBase ID
FBab0047080
Feature type
chromosomal_deletion
Also Known As
ΔGr64a-f, ΔGr64, Δ64a-f
Computed Breakpoints include
Features within 64A3--64A4 (Estimated cytology)
Genomic Maps
Sequence coordinates
3L:4,015,329..4,015,329 (Df(3L)DeltaGr64:bk1)
(Slone et al., 2007)
3L:4,040,635..4,040,635 (Df(3L)DeltaGr64:bk2)
(Slone et al., 2007)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{XP}Rcd5d06001
(Slone et al., 2007)
PBac{WH}f03449
(Slone et al., 2007)
Mutagen
FLPase
(Slone et al., 2007)
Class of aberration (relative to wild type)
chromosomal_deletion
(Slone et al., 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Slone et al., 2007)
Breakpoints
Causes alleles
Rcd5ΔGr64
(Slone et al., 2007)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Scer\FRT-mediated recombination between the two progenitor insertions has resulted in the deletion of the genomic sequence between them.

(Slone et al., 2007)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (12)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

When given a choice between trehalose and fructose, wild-type flies strongly prefer trehalose. In contrast, Df(3L)ΔGr64 mutant flies favor fructose.

Df(3L)ΔGr64 mutants lack behavioural and electrophysiological responses to sucrose, maltose and glucose.

In contrast to wild-type flies, virtually no action potentials are produced upon presentation of trehalose in Df(3L)ΔGr64 mutants.

(Jiao et al., 2008)

Df(3L)ΔGr64 is homozygous lethal.

P{t15.3.R1}/+, P{UAS-Rescue.R2}/+, Df(3L)ΔGr64/Df(3L)ΔGr64 flies show a drastic reduction in proboscis extension reflex for sucrose, glucose, trehalose, arabinose, and maltose. The introduction of P{UAS_Gr64abcdf.GFP} into this genetic background rescues the sugar-response phenotype.

Homozygous Df(3L)ΔGr64 mutant flies show as robust a response to fructose as do wild-type flies.

Homozygous Df(3L)ΔGr64 mutant flies show similar responses to bitter compounds as do wild-type flies.

(Slone et al., 2007)
Stocks (0)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (6)
References (12)