Aberration Dmel\Df(2R)Sema-2b-C4

General Information
Symbol	Dmel\Df(2R)Sema-2b-C4	Species	D. melanogaster
Name		FlyBase ID	FBab0047220
Feature type	chromosomal_deletion
Also Known As	Sema-2b^C4, FDD-0012943

Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	P{XP}d00791 (Wu et al., 2011) PBac{WH}f05499 (Wu et al., 2011)
Mutagen	FLPase (Wu et al., 2011)
Class of aberration (relative to progenitor)	chromosomal_deletion (Wu et al., 2011)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments	Scer\FRT-mediated recombination between the two progenitor insertions has resulted in the deletion of the genomic sequence between them. (Wu et al., 2011)
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Completely deleted	CG4398 (Wu et al., 2011) CG4409 (Wu et al., 2011) CG7848 (Wu et al., 2011) CG15925 (Wu et al., 2011) Menl-1 (Wu et al., 2011) Menl-2 (Wu et al., 2011) Sema-2b (Wu et al., 2011)
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
	CG4945 (Wu et al., 2011) CG6262 (Wu et al., 2011) CG7813 (Wu et al., 2011) CG15711 (Wu et al., 2011) CG15712 (Wu et al., 2011) CG33458 (Wu et al., 2011) CG33459 (Wu et al., 2011) CheB53a (Wu et al., 2011) CheB53b (Wu et al., 2011) DAT (Wu et al., 2011) loopin-1 (Wu et al., 2011) Sema-2a (Wu et al., 2011) S-Lap8 (Wu et al., 2011) Syn2 (Wu et al., 2011)
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Only 10.6% of hemisegments show disorganisation of the intermediate Fas2-positive longitudinal tract in Df(2R)Sema-2b-C4/Df(2R)B65 embryos. (Wu et al., 2011)
NOT in combination with other aberrations	46.3% of hemisegments show disorganisation of the intermediate Fas2-positive longitudinal tract in homozygous embryos. Chordotonal organs fail to elaborate their characteristic morphology within the central nervous system, most often terminating in a position that is lateral to where the intermediate Fas2-positive longitudinal tract normally forms and failing to form a continuous longitudinal branch between segments. Mutant larvae do reduce their speed significantly in response to vibration, but they show no head turning, in contrast to wild-type larvae. (Wu et al., 2011)
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	#078 (Sweeney et al., 2011) C4 (Wu et al., 2011) Df(2R)Sema-2b-C4 FDD-0012943 (Wu et al., 2011, Wu et al., 2011) Sema-2b^C4 (Sweeney et al., 2011, Wu et al., 2011, Wu et al., 2011)
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Sweeney et al., 2011, Neuron 72(5): 734--747 Secreted Semaphorins from Degenerating Larval ORN Axons Direct Adult Projection Neuron Dendrite Targeting. [FBrf0216932] Wu et al., 2011, Neuron 70(2): 281--298 A combinatorial semaphorin code instructs the initial steps of sensory circuit assembly in the Drosophila CNS. [FBrf0213571]
Supplementary material	Wu et al., 2011, Neuron 70(2): Supplemental Information. [FBrf0217575]