Aberration Dmel\Df(2R)k08901

General Information
Symbol	Dmel\Df(2R)k08901	Species	D. melanogaster
Name		FlyBase ID	FBab0047223
Feature type	chromosomal_deletion

Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Barbash, 2011.12.8)
Breakpoints
Causes alleles	l(2)k01209^k08901a (Barbash, 2011.12.8)
Carries alleles
Transposon Insertions	P{lacW}k08901b (Barbash, 2011.12.8) P{lacW}l(2)k01209^k08901a (Barbash, 2011.12.8)
Formalized genetic data
Genetic mapping information
Comments	The "k08901" line is deleted for the Lhr gene, demonstrating that this line contains a deletion. (Barbash, 2011.12.8) The breakpoints of Df(2R)k08901 may correspond to the two insertion sites reported in the flanking sequences (AQ034114 and AQ025874) for the "k08901" insertion line. The uncertainty is because it is not clear how many insertions are present in this line and whether there is an error in the reported site of P-element insertion in one of the flanking sequences. (FlyBase, 1996-)
Comments on Cytology

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Molecular Data
Completely deleted	Lhr (Barbash, 2011.12.8)
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Df(2R)k08901 rescues 7-8% of hybrid males to the pharate adult stage at 18[o]C (hybrids are the progeny of D. melanogaster Df(2R)k08901 females mated to D.mauritiana males). (Maheshwari and Barbash, 2012)
Stocks ( 1 )
Bloomington	10836 y¹ w^67c23; Df(2R)k08901, P{lacW}l(2)k01209^k08901a P{lacW}k08901b/CyO
Notes on Origin
Discoverer
	FlyBase curator comment: The "k08901" insertion line contains a deletion (Df(2R)k08901) (see FBrf0217415). It is not clear how many insertions are present in this line: although the 5' (AQ034114) and 3' (AQ025874) flanking sequences map 30kb apart, consistent with the presence of the deletion, the reported location of the P-element insertion site in the two flanking sequences appear to be incompatible if only one insertion is present. It is possible that there is one insertion in the line and that there is an error in the reported sequence data, or there may be two insertions in the line. Until more information is known, a separate insertion record exists in FlyBase for each flanking sequence: P{lacW}k08901b (FBti0025322) corresponds to the flanking sequence reported in AQ034114, P{lacW}l(2)k01209[k08901a] (FBti0006619) corresponds to the flanking sequence reported in AQ025874. (FlyBase, 1996-)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(2R)k08901 l(2)k01209 (Maheshwari and Barbash, 2012)
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Maheshwari and Barbash, 2012, PLoS Genet. 8(3): e1002597 Cis-by-Trans Regulatory Divergence Causes the Asymmetric Lethal Effects of an Ancestral Hybrid Incompatibility Gene. [FBrf0217900]
Personal communication to FlyBase	Barbash, 2011.12.8, k08901 line. k08901 line. [FBrf0217415] Levis, 2003.1.30, l(2)k08901 - two insertions? l(2)k08901 - two insertions? [FBrf0155448]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]