FB2025_01 , released February 20, 2025
Aberration: Dmel\Dp(3;3)Rdl
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General Information
Symbol
Dp(3;3)Rdl
Species
D. melanogaster
Name
FlyBase ID
FBab0047496
Feature type
tandem_duplication
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
natural population
(Remnant et al., 2013)
Class of aberration (relative to wild type)
tandem_duplication
(Remnant et al., 2013)
Class of aberration (relative to progenitor)
tandem_duplication
(Remnant et al., 2013)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Tandem duplication covering 113kb. Ectopic recombination between roo transposable elements was involved in generating the rearrangement. The first breakpoint occurred at the site of a roo long terminal repeat (LTR) in intron 7 of nwk, thus a 3' portion of nwk is duplicated. The second breakpoint occurred 113kb downstream, at the site of a roo LTR in intron 1 of GluRIB, thus a 5' portion of GluRIB is duplicated. A roo element is present in the duplication chromosome between the partially duplicated 5' portion of GluRIB and 3' portion of nwk. One copy of Rdl in the duplication is wild type while the second contains two point mutations (A301S and M360I).

(Remnant et al., 2013)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
CG4476
(Remnant et al., 2013)
CG4477
(Remnant et al., 2013)
CG4483
(Remnant et al., 2013)
Rdl
(Remnant et al., 2013)
Slc45-1
(Remnant et al., 2013)
Partially duplicated
GluRIB
(Remnant et al., 2013)
nwk
(Remnant et al., 2013)
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Mutant flies show 27-fold resistance to dieldrin compared to wild type. Mutant flies are significantly slower to recover from heat shock compared to wild type.

    (Remnant et al., 2013)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Tandem duplication identified in the Ral-318 and Ral-378 lines of the Drosophila Genomic Reference Panel (DGRP).

    (Remnant et al., 2013)
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Dp(3;3)Rdl
    Name Synonyms
    Secondary FlyBase IDs
      References (2)