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General Information
Symbol
Df(2L)mir-275-305-KO
Species
D. melanogaster
Name
FlyBase ID
FBab0047657
Feature type
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Deletion which removes the miRNA cluster containing the mir-275 and mir-305 miRNAs. A P1\loxP cassette containing the w+mW.hs marker is present at the site of the deletion.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations

Df(2L)mir-275-305-KO/Df(2L)BSC189 animals show partial lethality. Partial lethality due to a maternal effect is seen at the embryonic stage. Some lethality is seen during the larval stage.

Df(2L)mir-275-305-KO/Df(2L)BSC189 males and females have low fertility.

Df(2L)mir-275-305-KO/Df(2L)BSC189 males show a significant decrease in median lifespan compared to controls.

NOT in combination with other aberrations

Homozygotes show partial lethality. Some lethality is seen during the embryonic stage and some during the larval stage.

Homozygous males show a significant decrease in median lifespan compared to controls.

Homozygous males and females have low fertility.

Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Df(2L)mir-275-305-KO
Name Synonyms
Secondary FlyBase IDs
    References (1)