FB2022_03, released June 9, 2022

Aberration: Dmel\Df(2L)mir-306-79-9b-KO

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General Information
Symbol
Df(2L)mir-306-79-9b-KO
Species
D. melanogaster
Name
FlyBase ID
FBab0047662
Feature type
chromosomal_deletion
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
ends-out gene targeting
(Chen et al., 2014)
FLPase
(Chen et al., 2014)
I-SceI
(Chen et al., 2014)
Class of aberration (relative to wild type)
chromosomal_deletion
(Chen et al., 2014)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Chen et al., 2014)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
TI{TI}mir-306-79-9b-KO
(Chen et al., 2014)
Formalized genetic data
Genetic mapping information
Comments

Deletion which removes the miRNA cluster containing the mir-306, mir-79 and mir-9b miRNAs. A pair of inverted attP sites flanking a single P1\loxP site are present at the site of the deletion.

(Chen et al., 2014)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
mir-9b
(Chen et al., 2014)
mir-79
(Chen et al., 2014)
mir-306
(Chen et al., 2014)
Partially deleted
grp
(Chen et al., 2014)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Df(2L)mir-306-79-9b-KO/Df(2L)Exel6039 embryos show a significant increase in primordial germ cell number compared to controls.

    (Chen et al., 2014)
    NOT in combination with other aberrations

    Homozygous adults show significant defects in the hemolymph-brain barrier (as determined using a dye injection assay).

    Homozygous males and females are fertile.

    (Chen et al., 2014)
    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(2L)mir-306-79-9b-KO
    miR-306-79-9b KO
    (Simoes da Silva et al., 2019)
    Name Synonyms
    Secondary FlyBase IDs
      References (3)