FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(3R)hpRNA:1
Open Close
General Information
Symbol
Df(3R)hpRNA:1
Species
D. melanogaster
Name
FlyBase ID
FBab0048383
Feature type
chromosomal_deletion
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mi{ET1}CG4770MB01974
(Wen et al., 2015)
Mutagen
minos activity
(Wen et al., 2015)
Class of aberration (relative to wild type)
chromosomal_deletion
(Wen et al., 2015)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Wen et al., 2015)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

A 4,064 nt deletion.

(Wen et al., 2015)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
hpRNA:1
(Wen et al., 2015)
lncRNA:CR43282
(Wen et al., 2015)
lncRNA:CR46040
(Wen et al., 2015)
Partially deleted
CG4462
(Wen et al., 2015)
CG4770
(Wen et al., 2015)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Df(3R)hpRNA:1 mutant flies are lethal, but combination with either P{hpRNA:1+t8.6} or P{hpRNA:1-t7.9} (lacking a short region containing the hpRNA:1 gene) restores their viability. Flies carrying Df(3R)hpRNA:1 deletion together with the P{hpRNA:1-t7.9} construct, the ' hpRNA:1 mutant' combination, in trans to Df(3R)ED6025 show significantly reduced male fertility as well as decreased numbers of mature sperm in their seminal vesicles compared to their ' hpRNA:1 rescue' counterparts (carrying Df(3R)hpRNA:1 combined with P{hpRNA:1+t8.6}) and wild-type controls. The nuclear alignment as well as the investment cone alignment is perturbed in the hpRNA:1 mutant/Df(3R)ED6025 spermatocytes (and restored in the rescue males).

    (Wen et al., 2015)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Df(3R)hpRNA:1
    Name Synonyms
    Secondary FlyBase IDs
      References (1)