FB2025_01 , released February 20, 2025
Aberration: Dmel\Dp(2;2)SM5
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General Information
Symbol
Dp(2;2)SM5
Species
D. melanogaster
Name
FlyBase ID
FBab0049141
Genomic Maps
Sequence coordinates
2L:6,916,809..6,917,405 (Dp(2;2)SM5:bk1)
2R:6,917,406..6,917,406 (Dp(2;2)SM5:bk2)
2R:16,682,351..16,682,351 (Dp(2;2)SM5:bk3)
2R:16,682,827..16,682,827 (Dp(2;2)SM5:bk4)
2R:22,689,962..22,689,962 (Dp(2;2)SM5:bk5)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints

42D;53C;58F;[42D-42D];[53C-53C];[58F-58F];

Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

2R:16 ,682,351 (release 6 coordinates) is the 5' (proximal) end of a breakpoint associated with a deletion of 475bp of genomic sequence.

2R:16 ,682,827 (release 6 coordinates) is the 3' (distal) end of a breakpoint associated with a deletion of 475bp of genomic sequence.

The 2R:22 ,689,962 (release 6 coordinates) breakpoint is not associated with a duplication/deletion.

The 5' (proximal) side of the 42D breakpoint is present in two presumably identical copies juxtaposed to low-complexity sequence and maps to the 2L:6 ,916,809-6,917,405 interval.

The sequence on the distal side of the 42D breakpoint suggests CG30158 is disrupted.

This is the 3' (distal) breakpoint of the 42D break.

A second, intact copy of lncRNA:CR44763 is present elsewhere on SM5.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Dp(2;2)SM5 represents a complex rearrangement that includes a duplication of two chromosomal segments as well as inversions. The two duplicated segments lie adjacent to one another: one segment duplicates 42A7-42E1 while the other duplicates 58A4-59A2. The two copies of the two segments have a mirror-image arrangement with heterochromatin separating them. The two duplicated segments are joined to the end of the 53D1-42E1 segment, which is inverted relative to the progenitor as part of the complex rearrangement. The 58A4;42A7 inversion breakpoint is present within the duplication because it was present on the progenitor chromosome in the region that was duplicated.

    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (1)