Allele Dmel\Abd-B^iab9-x23-1

General Information
Symbol	Dmel\Abd-B^iab9-x23-1	Species	D. melanogaster
Name		FlyBase ID	FBal0000144
Feature type	allele	Associated gene	Dmel\Abd-B
Also Known As	Abd-B^X23-1, x23-1

Allele class
Mutagen	X ray
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	X ray (Kuhn et al., 1993)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	viable (Sanchez-Herrero and Crosby, 1988) visible \| dominant (Kuhn et al., 1993) visible \| homeotic \| recessive (Sanchez-Herrero and Crosby, 1988) visible \| recessive (Kuhn et al., 1993)
Phenotype Manifest In
	embryonic abdominal segment 9 (Sanchez-Herrero and Crosby, 1988) epiproct \| somatic clone (Foronda et al., 2006) female accessory gland (with Abd-B^Uab-1) (Foronda et al., 2006) female analia (Sanchez-Herrero and Crosby, 1988) female genitalia (Sanchez-Herrero and Crosby, 1988) female genitalia (with Abd-B^Uab-1) (Foronda et al., 2006) genitalia (Kuhn et al., 1993) leg \| ectopic \| somatic clone (Foronda et al., 2006) male analia (Sanchez-Herrero and Crosby, 1988) male genitalia (Sanchez-Herrero and Crosby, 1988) male genitalia (with Abd-B^Uab-1) (Foronda et al., 2006) parasegment 14 (Sanchez-Herrero and Crosby, 1988) spermathecum \| ectopic (with Abd-B^Uab-1) (Foronda et al., 2006)
Detailed Description
	Statement Reference Abd-B^iab9-x23-1 clones exhibit transformation of the male A9 tissue into leg tissue in the adult. Abd-B^iab9-x23-1/Abd-B^Uab-1 male flies lack internal genitalia, while female genitalia is abnormal. A common feature of these females is the absence of parovaria, and in about half of these, three or even four spermathecae instead of the normal two are observed. Supernumerary spermathecae are also detected in Abd-B^iab9-x23-1/Abd-B^Uab-1 clones. In a few females, duplications of part of the internal genitalia are observed. (Foronda et al., 2006) Adult homozygous males have 6 normal abdominal segments. Males and females lack genitalia. Heterozygotes with Abd-B^iab9-tuh-3 exhibit genital defects to a moderate degree. No effect on penetrance of head defect phenotype, when in trans with Abd-B^iab9-tuh-3. (Kuhn et al., 1993) Male and female genitalia and analia are missing or abnormal in homozygotes. Parasegment 14 is partially transformed into parasegment 13, and there is a rudimentary setal belt in A9 in homozygous embryos. (Sanchez-Herrero and Crosby, 1988)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Complements	Abd-B³⁸⁰ (Sanchez-Herrero and Crosby, 1988) Abd-B^F (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-D6 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-D14 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-D15 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-rv82 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-rv89 (Sanchez-Herrero and Crosby, 1988) Abd-B^M2 (Sanchez-Herrero and Crosby, 1988) Abd-B^M3 (Sanchez-Herrero and Crosby, 1988) Abd-B^M4 (Sanchez-Herrero and Crosby, 1988) Abd-B^M5 (Sanchez-Herrero and Crosby, 1988) Abd-B^M6 (Sanchez-Herrero and Crosby, 1988) Abd-B^M7 (Sanchez-Herrero and Crosby, 1988) Abd-B^M9 (Sanchez-Herrero and Crosby, 1988) Abd-B^R (Sanchez-Herrero and Crosby, 1988) Abd-B^S1 (Sanchez-Herrero and Crosby, 1988) Abd-B^S2 (Sanchez-Herrero and Crosby, 1988) Abd-B^S5 (Sanchez-Herrero and Crosby, 1988) Abd-B^S8 (Sanchez-Herrero and Crosby, 1988) Abd-B^S9 (Sanchez-Herrero and Crosby, 1988)
Fails to complement	Abd-B²⁹⁷ (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-D3 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-D16 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-rv5 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-rv10 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab8-rv75 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab9-48 (Sanchez-Herrero and Crosby, 1988) Abd-B^iab9-65 (Sanchez-Herrero and Crosby, 1988) Abd-B^M1 (Sanchez-Herrero and Crosby, 1988) Abd-B^M8 (Sanchez-Herrero and Crosby, 1988) Abd-B^S4 (Sanchez-Herrero and Crosby, 1988) Abd-B^S7 (Sanchez-Herrero and Crosby, 1988) Abd-B^S11 (Sanchez-Herrero and Crosby, 1988)
Comments	Complements iab-5 and iab-6 alleles. (Sanchez-Herrero and Crosby, 1988)
Stocks ( 0 )

Notes on Origin
Discoverer	Casanova.

Comments
	Encodes the r protein of Abd-B. (Jones and McGinnis, 1993) m⁺ r^- mutant. (Kuhn et al., 1993) abd-A expression in parasegments 14 and 15, after retraction of germ band. m⁺r^-; coincides with wild type r element function (FBrf0047944; FBrf0047933; FBrf0047945). (Macias et al., 1990)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	Abd-B^iab9-x23-1 Abd-B^rz23-1 Abd-B^X23-1 (Foronda et al., 2006) Abd-B^x23-1 (Estrada et al., 2002, Jones and McGinnis, 1993) Abd-Br^z23-1 (Macias et al., 1990) iab9^x23-1 (Mack et al., 1997, ) x23-1 (Kuhn et al., 1993, Sanchez-Herrero and Crosby, 1988, )
Name Synonym
Secondary FlyBase IDs
	FBal0028694
References ( 7 )
Research paper	Foronda et al., 2006, Development 133(1): 117--127 Requirement of abdominal-A and Abdominal-B in the developing genitalia of Drosophila breaks the posterior downregulation rule. [FBrf0190286] Estrada et al., 2002, Development 129(22): 5195--5204 Genetic and molecular characterization of a novel iab-8 regulatory domain in the Abdominal-B gene of Drosophila melanogaster. [FBrf0151935] Mack et al., 1997, Genetics 147(2): 679--688 Mobile element 297 in the Abd-B gene of Drosophila melanogaster, not Delta 88, is responsible for the tuh-3 mutation. [FBrf0098834] Jones and McGinnis, 1993, Genes Dev. 7(2): 229--240 The regulation of empty spiracles by Abdominal-B mediates an abdominal segment identity function. [FBrf0058524] Kuhn et al., 1993, Genetics 133(3): 593--604 Tumorous-head (tuh-1; tuh-3) modulates Abd-B Bithorax-complex functions in Drosophila melanogaster. [FBrf0058571] Macias et al., 1990, Development 110: 1197--1207 Expression and regulation of the abd-A gene of Drosophila. [FBrf0051550] Sanchez-Herrero and Crosby, 1988, EMBO J. 7(7): 2163--2173 The Abdominal-B gene of Drosophila melanogaster: overlapping transcripts exhibit two different spatial distributions. [FBrf0047933]

Allele Dmel\Abd-Biab9-x23-1

Allele Dmel\Abd-B^iab9-x23-1