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General Information
Symbol
Dmel\ac1
Species
D. melanogaster
Name
FlyBase ID
FBal0000160
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

A deficiency extending from a point between kb 64.9 and 63.5, which is approximately 5 kb upstream from the presumptive ac transcription unit, to the left to approximately kb 82. Deletion.

Deletion for kb 84 to 64; includes y.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies homozygous or hemizygous for ac1 lack all four dorsocentral bristles. No phenotypes are seen in heterozygotes.

The total number of bristles on the basitarsi of the second legs is reduced. The number of bractless bristles on the basitarsi remains normal. Significantly more bristles are missing from the anterior side of the basitarsus than from the posterior side. One or the other of the distal sensilla is sometimes missing, and an ectopic sensillum sometimes forms proximally between bristle rows 3 and 4.

Posterior dorsocentral bristles missing; also posterior supra-alar and anterior vertical bristles frequently missing. Anterior dorsocentrals displaced anteriorly (FBrf0020635). Garcia-Bellido (FBrf0033191) finds anterior dorsocentral bristles more strongly decreased than posterior dorsocentrals. Hairs usually fewer near position of posterior dorsocentrals; interocellar hairs invariably fewer, typically absent. Eyes partly devoid of hairs. Trichomes unaffected. Limited nonautonomy near the borders of somatic spots with respect both to numbers and positions of bristles and hairs (FBrf0009297; FBrf0013897; FBrf0020635).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

ac1 has visible | recessive | adult stage phenotype, suppressible | partially by Bx2

Suppressor of
Statement
Reference

ac1/sc1 is a suppressor of visible | heat sensitive phenotype of HC2.hs

Other
Statement
Reference
Phenotype Manifest In
Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference

ac1 has anterior dorsocentral bristle phenotype, non-suppressible by Bx2

ac1 has phenotype, non-suppressible by su(Hw)2

Suppressor of
Statement
Reference

ac1/sc1 is a suppressor of wing vein | ectopic | heat sensitive phenotype of HC2.hs

ac1/sc1 is a suppressor of wing | heat sensitive phenotype of HC2.hs

ac1 is a suppressor of phenotype of h1

Other
Additional Comments
Genetic Interactions
Statement
Reference

Flies carrying one copy of ac1 and one copy of Bxhdp58-1 lack the anterior dorsocentral bristles. No phenotypes are observed in either heterozygote alone.

Flies carrying one copy of ac1 and one copy of Bxhdp185-1 lack the anterior dorsocentral bristles. No phenotypes are observed in either heterozygote alone.

Flies carrying one copy of ac1 and one copy of BxhdpR590 lack the anterior dorsocentral bristles. No phenotypes are observed in either heterozygote alone.

Homozygous or hemizygous Bx2 suppresses the anterior dorsocentral bristle loss seen in homozygous or hemizygous ac1 mutants. The double mutant flies still show posterior dorsocentral bristle loss.

Homozygous or hemizygous Bx1002 suppresses the anterior dorsocentral bristle loss seen in homozygous or hemizygous ac1 mutants. The double mutant flies still show posterior dorsocentral bristle loss.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (1)
Stocks (32)
Notes on Origin
Discoverer

Weinstein, 3rd Feb. 1916.

Arose on: yunspecified.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (12)